Evidence map›Paper›PMID 24804217›Full record

ReviewBioMed research international2014

In silico modeling of the immune system: cellular and molecular scale approaches.

Mariagrazia Belfiore, Marzio Pennisi, Giuseppina Aricò, Simone Ronsisvalle, Francesco Pappalardo

Abstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mariagrazia BelfioreDepartment of Drug Sciences, University of Catania, V.le A. Doria 6, 95125 Catania, Italy.
Marzio PennisiDepartment of Mathematics and Computer Science, University of Catania, V.le A. Doria 6, 95125 Catania, Italy.ORCID 0000-0003-0231-7653
Giuseppina AricòDepartment of Drug Sciences, University of Catania, V.le A. Doria 6, 95125 Catania, Italy.
Simone RonsisvalleDepartment of Drug Sciences, University of Catania, V.le A. Doria 6, 95125 Catania, Italy.
Francesco PappalardoDepartment of Drug Sciences, University of Catania, V.le A. Doria 6, 95125 Catania, Italy.ORCID 0000-0003-1668-3320

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The revolutions in biotechnology and information technology have produced clinical data, which complement biological data. These data enable detailed descriptions of various healthy and diseased states and responses to therapies. For the investigation of the physiology and pathology of the immune responses, computer and mathematical models have been used in the last decades, enabling the representation of biological processes. In this modeling effort, a major issue is represented by the communication between models that work at cellular and molecular level, that is, multiscale representation. Here we sketch some attempts to model immune system dynamics at both levels.

Indexed as

Computer SimulationModels, ImmunologicalAnimalsHumans

Identifiers

PMID24804217
PMCPMC3997136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.