ReviewMediterranean journal of hematology and infectious diseases2014
Tuberculosis in patients with haematological malignancies.
Review in Mediterranean journal of hematology and infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Burden of tuberculosis among patients with cancer: a comprehensive systematic review and meta-analysis of global data.JNCI cancer spectrum · 2025Pooled it
- Application of Metagenomic Next-Generation Sequencing inFrontiers in medicine · 2022Pooled it
- Comparison of diagnostic accuracy and sensitivity of Kinyoun and auramine-rhodamine stains in detecting mycobacteria from specimen smears.Microbiology spectrum · 2026Article
- Active Tuberculosis Risk Associated with Malignancies: A 4-Year Retrospective Study in a Tertiary Care Hospital.South Asian journal of cancer · 2025Article
- Coexistence of Hodgkin's Lymphoma and Tuberculosis in Two Young Adults: Diagnostic and Management Challenges.Cureus · 2025Article
- Management of latent tuberculosis infection (LTBI) in adult patients with newly diagnosed acute leukemia: results of a survey among Italian centers belonging to SEIFEM (Sorveglianza Epidemiologica Infezioni nelle Emopatie) group.Annals of hematology · 2024Article
- Latent tuberculosis infection detected by quantiferon-TB assay in patients with multiple myeloma receiving novel drugs: focus on reactivation prophylaxis in a retrospective, single-center study.Annals of hematology · 2024Article
- Acute Leukemia and Latent Tuberculosis Infection in Italy: Quantiferon-Tb Test Screening in a Low Tuberculosis Incidence Country.Mediterranean journal of hematology and infectious diseases · 2024Article
- Case report: Difficult diagnosis ofFrontiers in oncology · 2024Article
- Implementation of a Routine Screening Program for Latent Tuberculosis Infection among Patients with Acute Leukemia at a Canadian Cancer Center.Current oncology (Toronto, Ont.) · 2022Article
- Prevalence of latent tuberculosis in patients with hematological neoplasms in a cancer referral hospital in Mexico City.BMC infectious diseases · 2021Article
- Bacterial nucleomodulins and cancer: An unresolved enigma.Translational oncology · 2021Review
- Increased Risk of Lymphoma in Men or the Elderly Infected with Tuberculosis.Mediterranean journal of hematology and infectious diseases · 2021Article
- Features of indeterminate results of QuantiFERON-TB Gold In-Tube test in patients with haematological malignancies.Therapeutic advances in hematology · 2021Article
- Incidence of and Risk Factors for Tuberculosis among Cancer Patients in Endemic Area: A Regional Cohort Study.Asian Pacific journal of cancer prevention : APJCP · 2020Article
- Comparison between the InterferonPulmonary medicine · 2020Article
- An incidental finding of chronic lymphocytic leukaemia in a patient with pulmonary tuberculosis.Southern African journal of infectious diseases · 2020Article
- Urban Air Pollution Particulates Suppress Human T-Cell Responses toInternational journal of environmental research and public health · 2019Article
- Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: A case report.Medicine · 2017Article
- Infections Caused by Mycobacterium tuberculosis in Recipients of Hematopoietic Stem Cell Transplantation.Frontiers in oncology · 2014Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tuberculosis (TB) is an infectious disease that causes more than 1 million deaths worldwide every year. In addition, it is estimated that one third of the world population is infected with M. tuberculosis in a latent state, which involves an eventual risk of progressing to active TB disease. Patients with immunodeficiencies, such as those suffering from haematological malignancies, have a greater risk of progressing to TB disease once infected. It is estimated that the Relative Risk of TB disease in patients with hematologic malignancies is 2-40 times that of the general population. The diagnosis of TB in these patients is often challenging as they often present clinical characteristics that are distinct to those of patients without any other underlying disease. Mortality due to TB is higher. Therefore, it is recommended to diagnose latent TB infection and consider preventive therapy that could avoid the progression from a latent state to active TB disease. There are currently two methods for diagnosing latent TB infection: the Tuberculin Skin Test (TST) and the Interferon-Gamma Release Assays (IGRA). Due to the lack of sensitivity in patients with immunodeficient conditions, a combined TST-IGRA testing is probably the best way for latent TB diagnosis in order to gain sensitivity. Treatment of latent TB infection and TB disease should follow the general principles to that in the general population.
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Registered trials
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