ArticleOxidative medicine and cellular longevity2014
Antioxidant bioactivity of Samsum ant (Pachycondyla sennaarensis) venom protects against CCL₄-induced nephrotoxicity in mice.
Article in Oxidative medicine and cellular longevity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- Rutin outperforms gallic acid in mitigating carbon tetrachloride-induced nephrotoxicity: Integrated in silico (docking, MD simulations, DFT) and in vivo mechanistic validation.Toxicology reports · 2026Article
- Nootkatone Supplementation Attenuates Carbon Tetrachloride Exposure-Induced Nephrotoxicity in Mice.Antioxidants (Basel, Switzerland) · 2023Article
- Antioxidative potential and ameliorative effects of green lentil (Frontiers in nutrition · 2022Article
- Evaluation of the in vivo antihypertensive effect and antioxidant activity of HL-7 and HL-10 peptide in mice.Molecular biology reports · 2021Article
- Samsum ant venom protects against carbon tetrachloride-induced acute spleen toxicity in vivo.Environmental science and pollution research international · 2021Article
- Bioactive Tryptophan-Based Copper Complex with Auxiliary β-Carboline Spectacle Potential on Human Breast Cancer Cells: In Vitro and In Vivo Studies.Molecules (Basel, Switzerland) · 2021Article
- Folic acid and melatonin mitigate diabetic nephropathy in rats via inhibition of oxidative stress.Nutrition & metabolism · 2020Article
- Thymoquinone ameliorates Pachycondyla sennaarensis venom-induced acute toxic shock in male rats.BMC pharmacology & toxicology · 2019Article
- Biosynthesized Silver Nanoparticle (AgNP) FromFrontiers in microbiology · 2019Article
- Samsum ant venom modulates the immune response and redox status at the acute toxic doseThe journal of venomous animals and toxins including tropical diseases · 2019Article
- Copper Mediates Anti-Inflammatory and Antifibrotic Activity of Gleevec in Hepatocellular Carcinoma-Induced Male Rats.Canadian journal of gastroenterology & hepatology · 2019Article
- Evaluation of novel factor Xa inhibitors from Oxya chinensis sinuosa with anti-platelet aggregation activity.Scientific reports · 2017Article
- Inhibition of platelet aggregation and thrombosis by indole alkaloids isolated from the edible insect Protaetia brevitarsis seulensis (Kolbe).Journal of cellular and molecular medicine · 2017Article
- Potential effects of samsum ant, Brachyponera sennaarensis, venom on TNF-α/NF-κB mediated inflammation in CCL4-toxicity in vivo.Lipids in health and disease · 2016Article
- Camel milk peptide improves wound healing in diabetic rats by orchestrating the redox status and immune response.Lipids in health and disease · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess whether SAV could influence the effects of carbon tetrachloride (CCL4) exposure, mice were treated with SAV in doses of 100, 200, 300 and 400 μg/kg body weight and the effects on oxidative status and kidney function were studied. Serum levels of creatinine, malondialdehyde (MDA), and blood urea, together with renal and hepatic levels of MDA, glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT) were quantified in order to evaluate antioxidant activity. Results showed that the group injected with CCL4 exhibited significantly higher levels of oxidative stress markers, MDA, and significantly lower concentrations of GSH, SOD and catalase. SAV was found to significantly improve these oxidative markers, occasionally, in a dose-dependent manner. Furthermore, treatment with SAV was associated with the same behaviour in respect to kidney functions which had previously been impaired by CCL4. Histopathological examination demonstrated that SAV, in different groups, improved the renal tissue damage induced by CCL4 and histological scores confirmed that significant improvements were obtained after treatment with SAV, particularly with the lowest dose (100 μg/kg body weight). In conclusion, SAV has the potential capability to restore oxidative stability and to improve kidney functions after CCL4 acute injury.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.