Evidence map›Paper›PMID 24803810›Full record

ArticleWorld journal of gastroenterology2014

NAFLD prevalence differs among hispanic subgroups: the Multi-Ethnic Study of Atherosclerosis.

Michael Wayne Fleischman, Matthew Budoff, Ifran Zeb, Dong Li, Temitope Foster

Registry-linked trialOpen access · hybridAbstract readComparative StudyMulticenter Study
In one paragraph

Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06130202 (Echocardiographic Findings as Markers of Subclinical Cardiac Dysfunction in Patients With Non-Alcoholic Fatty Liver Disease), which is not on this map. Cited by 72 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06130202 unknown statusnot on this mapstarted 2023, after this paper: background citation

Echocardiographic Findings as Markers of Subclinical Cardiac Dysfunction in Patients With Non-Alcoholic Fatty Liver Disease

TypeobservationalSponsorAssiut UniversityRan2023 to 2025Enrolled165ConditionsNAFLDArmsEchocardiographic findings
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 3 syntheses or guidelines pooled it, 134 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
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  14. Global Epidemiological Impact of PNPLA3 I148M on Liver Disease.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Review
  15. Characterization of an At-Risk Population for Nonalcoholic Fatty Liver Disease (NAFLD) in a Primary Care Setting Along the U.S.-Mexico Border.Journal of transcultural nursing : official journal of the Transcultural Nursing Society · 2025
    Review
  16. Skeletal Muscle and Cardiovascular Health.Advances in experimental medicine and biology · 2025
    Review
  17. Article
  18. Article
  19. Review
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michael Wayne FleischmanMichael Wayne Fleischman, Temitope Foster, Division of Digestive Diseases, Department of Medicine, Emory University, Atlanta, GA 30324, United States.
Matthew BudoffMichael Wayne Fleischman, Temitope Foster, Division of Digestive Diseases, Department of Medicine, Emory University, Atlanta, GA 30324, United States.
Ifran ZebMichael Wayne Fleischman, Temitope Foster, Division of Digestive Diseases, Department of Medicine, Emory University, Atlanta, GA 30324, United States.
Dong LiMichael Wayne Fleischman, Temitope Foster, Division of Digestive Diseases, Department of Medicine, Emory University, Atlanta, GA 30324, United States.
Temitope FosterMichael Wayne Fleischman, Temitope Foster, Division of Digestive Diseases, Department of Medicine, Emory University, Atlanta, GA 30324, United States.
Emory University · US

Funding

Ventricular Size and Valve Calcification Measures by CTR01HL071739 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI BUDOFF, MATTHEW J · 2003 to 2010
$2.0M
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095165 · HC · WAKE FOREST UNIVERSITY · PI BURKE, GREGORY L · 1999 to 2001
$616k
Enhancing immune reconstitution after implantation of postnatal allogeneic thymusR21HL095165 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CROOKS, GAY M · 2008 to 2009
$440k
SUBCLINICAL CARDIOVASCULAR DISEASE COORDINATING CENTER-N01HC95159-268095159N01HC095159 · HC · UNIVERSITY OF WASHINGTON · PI KRONMAL, RICHARD A · 1999 to 2006
$304k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--EBCT READINGN01HC95169 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · 2007 to 2008
$167k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--EBCT READINGN01HC095169 · HC · LA BIOMED RES INST/ HARBOR UCLA MED CTR · PI DETRANO, ROBERT · 1999 to 2001
$124k
NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095169NHLBI NIH HHS N01-HC-95159NHLBI NIH HHS N01-HC-95165NHLBI NIH HHS N01 HC95169NHLBI NIH HHS R01 HL071739
6 · The paper itself

Abstract

aimTo compare prevalence rates of non-alcoholic fatty liver disease (NAFLD) between Hispanics of Mexican origin and Hispanics of Dominican and Puerto Rican origin.

methodsWe evaluated prevalence rates of NAFLD between the two largest sub-populations of Hispanics in the United States; Hispanics of Mexican origin and Hispanics of Caribbean origin (Dominican and Puerto Rican), in the multi-ethnic study of atherosclerosis (MESA) cohort. MESA is a large, population based, multi-center cohort study comprised of 6814 healthy Caucasian, African-American, Hispanic, and Asian men and women aged 45-84. We utilized the baseline serum, anthropometric and radiographic measurements obtained between 2000 and 2002. NAFLD was measured via computed tomography scan and was defined as liver/spleen attenuation ratio < 1.

resultsThere were 788 Hispanic participants included in the study after exclusions. The prevalence of NAFLD was 29% (n = 225). Hispanics of Mexican origin had a significantly higher prevalence of NAFLD (33%), compared to Hispanics of Dominican origin (16%), (P < 0.01) and Hispanics of Puerto Rican origin (18%), (P < 0.01). After controlling for age, sex, BMI, waist circumference, hypertension, serum HDL, triglyceride and CRP level and insulin resistance, Hispanics of Mexican origin remained significantly more likely to have NAFLD than those of Dominican and Puerto Rican origin.

conclusionUnited States Hispanics of Mexican origin have a significantly higher prevalence of NAFLD when compared to United States Hispanics of Dominican or Puerto Rican origin after controlling for known risk factors. Care should be taken when performing risk assessment in Hispanic populations not to make assumptions of homogeneity.

Indexed as

Hispanic or LatinoAgedAged, 80 and overAtherosclerosisBiomarkersChi-Square DistributionDominican RepublicFemaleHumansInflammation MediatorsLipidsLogistic ModelsMaleMexican AmericansMiddle AgedMultivariate AnalysisBiomarkersInflammation MediatorsLipidsHispanic subpopulationsNon-alcoholic fatty liver diseasePrevalence

Identifiers

PMID24803810
PMCPMC4009531
OpenAlexW2058919942

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.