Evidence map›Paper›PMID 24803672›Full record

ArticleNucleic acids research2014

STarMir: a web server for prediction of microRNA binding sites.

William Rennie, Chaochun Liu, C Steven Carmack, Adam Wolenc, Shaveta Kanoria, Jun Lu, Dang Long, Ye Ding

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 136 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Sfold Tools for MicroRNA Target Prediction.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  5. miRNA Target Prediction: An Overview of the Past and Current Tools.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Epigenetic Regulation ofInternational journal of molecular sciences · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. BLV-miR-B1-5p PromotesAnimals : an open access journal from MDPI · 2023
    Article
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

William RennieWadsworth Center, New York State Department of Health, Center for Medical Science, 150 New Scotland Avenue, Albany, NY 12208, USA.
Chaochun LiuWadsworth Center, New York State Department of Health, Center for Medical Science, 150 New Scotland Avenue, Albany, NY 12208, USA.
C Steven CarmackWadsworth Center, New York State Department of Health, Center for Medical Science, 150 New Scotland Avenue, Albany, NY 12208, USA.
Adam WolencWadsworth Center, New York State Department of Health, Center for Medical Science, 150 New Scotland Avenue, Albany, NY 12208, USA.
Shaveta KanoriaWadsworth Center, New York State Department of Health, Center for Medical Science, 150 New Scotland Avenue, Albany, NY 12208, USA.
Jun LuDepartment of Genetics and Yale Stem Cell Center, Yale University, New Haven, CT 06520, USA.
Dang LongWadsworth Center, New York State Department of Health, Center for Medical Science, 150 New Scotland Avenue, Albany, NY 12208, USA.
Ye DingWadsworth Center, New York State Department of Health, Center for Medical Science, 150 New Scotland Avenue, Albany, NY 12208, USA yding@wadsworth.org.
New York State Department of Health · USWadsworth Center · USYale University · US

Funding

Novel Approaches to Mammalian MicroRNA Target PredictionR01GM099811 · NIGMS · WADSWORTH CENTER · PI DING, YE, LU, JUN · 2012 to 2015
$2.4M
The role of microRNAs in leukemic initiation and maintenanceR01CA149109 · NCI · YALE UNIVERSITY · PI LU, JUN · 2011 to 2015
$1.7M
NCI NIH HHS R01CA149109NIGMS NIH HHS GM099811NIGMS NIH HHS R01 GM099811
6 · The paper itself

Abstract

STarMir web server predicts microRNA (miRNA) binding sites on a target ribonucleic acid (RNA). STarMir is an implementation of logistic prediction models developed with miRNA binding data from crosslinking immunoprecipitation (CLIP) studies (Liu,C., Mallick, B., Long, D., Rennie, W.A., Wolenc, A., Carmack, C.S. and Ding, Y. (2013). CLIP-based prediction of mammalian microRNA binding sites. Nucleic Acids Res., 41(14), e138). In both intra-dataset and inter-dataset validations, the models showed major improvements over established algorithms in predictions of both seed and seedless sites. General applicability of the models was indicated by good performance in cross-species validations. The input data for STarMir is processed by the web server to perform prediction of miRNA binding sites, compute comprehensive sequence, thermodynamic and target structure features and a logistic probability as a measure of confidence for each predicted site. For each of seed and seedless sites and for all three regions of a mRNA (3' UTR, CDS and 5' UTR), STarMir output includes the computed binding site features, the logistic probability and a publication-quality diagram of the predicted miRNA:target hybrid. The prediction results are available through both an interactive viewer and downloadable text files. As an application module of the Sfold RNA package (http://sfold.wadsworth.org), STarMir is freely available to all at http://sfold.wadsworth.org/starmir.html.

Indexed as

SoftwareAnimalsBinding SitesHumansInternetMiceMicroRNAsRNA, MessengerSequence Analysis, RNAMicroRNAsRNA, Messenger

Identifiers

PMID24803672
PMCPMC4086099
OpenAlexW2113801629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.