Evidence map›Paper›PMID 24803345›Full record

ArticleWorld journal of surgery2014

High survival in patients operated for small isolated liver metastases from gastric cancer: a multi-institutional study.

Koji Komeda, Michihiro Hayashi, Shoji Kubo, Hiroaki Nagano, Takuya Nakai, Masaki Kaibori, Hiroshi Wada, Shigekazu Takemura, Masahiko Kinoshita, Chikato Koga and 6 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in World journal of surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
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  7. Article
  8. Article
  9. Review
  10. Article
  11. Current management of liver metastases from gastric cancer: what is common practice? New challenge of EORTC and JCOG.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2017
    Article
  12. Systemic chemotherapy as a main strategy for liver metastases from gastric cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Koji KomedaDepartment of General and Gastroenterological Surgery, Osaka Medical College Hospital, Takatsuki, 2-7 Daigaku-machi, Takatsuki City, Osaka, 569-8686, Japan, sur115@poh.osaka-med.ac.jp.
Michihiro Hayashi
Shoji Kubo
Hiroaki Nagano
Takuya Nakai
Masaki Kaibori
Hiroshi Wada
Shigekazu Takemura
Masahiko Kinoshita
Chikato Koga
Masataka Matsumoto
Tatsuma Sakaguchi
Yoshihiro Inoue
Fumitoshi Hirokawa
A-Hon Kwon
Kazuhisa Uchiyama
Osaka Medical and Pharmaceutical University · JPKansai Medical University · JPOsaka City University · JPOsaka University · JPKindai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough several studies have reported the outcomes of surgery for the treatment of liver metastases of gastric cancer (GLM), indications for liver resection for gastric metastases remain controversial. This study was designed to identify prognostic determinants that identify operable hepatic metastases from gastric cancer and to evaluate the actual targets of surgical therapy.

methodsRetrospective analysis was performed on outcomes for 24 consecutive patients at five institutions who underwent gastrectomy for gastric cancer followed by curative hepatectomy for GLM between 2000 and June 2012.

resultsOverall 5-year survival and median survival were 40.1 % and 22.3 months, respectively. Uni- and multivariate analyses showed that liver metastatic tumour size less than 5 cm was the most important predictor of overall survival (OS, p = 0.03). Four patients survived >5 years. Repeat hepatectomy was performed in three patients. Two of these patients have remained disease-free since the repeat hepatectomy.

conclusionsGLM patients with metastatic tumour diameter less than 5 cm maximum are the best candidates for hepatectomy. Hepatic resection should be considered as an option for gastric cancer patients with liver metastases.

Indexed as

AdenocarcinomaAdultAgedAnalysis of VarianceFemaleGastrectomyHepatectomyHumansLiver NeoplasmsMaleMiddle AgedPrognosisRetrospective StudiesStomach NeoplasmsSurvival RateTumor Burden

Identifiers

PMID24803345
OpenAlexW2063396176

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.