ArticleParasitology research2014
First report of an Acanthamoeba genotype T13 isolate as etiological agent of a keratitis in humans.
Article in Parasitology research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Genotype distribution of Acanthamoeba in keratitis: a systematic review.Parasitology research · 2021Pooled it
- Molecular evidence for trichomonads and acanthamoebae in cloacal samples of synanthropic waterfowl.Parasitology research · 2025Article
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- Distribution and Current State of Molecular Genetic Characterization in Pathogenic Free-Living Amoebae.Pathogens (Basel, Switzerland) · 2022Review
- Opportunistic free-living amoebal pathogens.Pathogens and global health · 2022Article
- High oxygen concentrations inhibit Acanthamoeba spp.Parasitology research · 2021Article
- Detection and Identification ofJournal of clinical microbiology · 2021Article
- An annotated checklist of the eukaryotic parasites of humans, exclusive of fungi and algae.ZooKeys · 2021Article
- Combined Amoebicidal Effect of Atorvastatin and Commercial Eye Drops againstPathogens (Basel, Switzerland) · 2020Article
- Update on Acanthamoeba jacobsi genotype T15, including full-length 18S rDNA molecular phylogeny.Parasitology research · 2017Article
- Free-Living Amoebae as Hosts for and Vectors of Intracellular Microorganisms with Public Health Significance.Viruses · 2017Review
- Acanthamoeba genotypes T3 and T4 as causative agents of amoebic keratitis in Mexico.Parasitology research · 2016Article
- Occurrence and molecular characterization of free-living amoeba species (Acanthamoeba, Hartmannella, and Saccamoeba limax) in various surface water resources of Iran.Parasitology research · 2015Article
- The role of domestic tap water on Acanthamoeba keratitis in non-contact lens wearers and validation of laboratory methods.Parasitology research · 2015Article
- Acanthamoeba misidentification and multiple labels: redefining genotypes T16, T19, and T20 and proposal for Acanthamoeba micheli sp. nov. (genotype T19).Parasitology research · 2015Article
- Occurrence of pathogenic Acanthamoeba genotypes in nasal swabs of cancer patients in Iran.Parasitology research · 2015Article
- Molecular Characterization of Pathogenic Acanthamoeba Isolated from Drinking and Recreational water in East Azerbaijan, Northwest Iran.Environmental health insights · 2015Article
- Some secrets are revealed: parasitic keratitis amoebae as vectors of the scarcely described pandoraviruses to humans.Parasitology research · 2014Article
- Twenty years of acanthamoeba diagnostics in Austria.The Journal of eukaryotic microbiologyReview
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3 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Several strains of free-living amoebae (FLA) belonging to the genus Acanthamoeba are able to cause a painful sight-threatening disease of the cornea designated as Acanthamoeba keratitis (AK). In this case report, a 22-year-old woman, wearer of soft contact lenses, was treated after the initial examination, and follow-up laboratory results led to the diagnosis of Acanthamoeba keratitis. The patient recovered under the targeted therapy, demonstrating that the acanthamoebae were the etiological agents of the keratitis in this case. The acanthamoebae belonged morphologically to group II. Genotyping of the causative Acanthamoeba strain based on sequences of the PCR amplimer ASA.S1 amplified from 18S ribosomal DNA by using the genus-specific primers JDP1 and JDP2 followed. The phylogenetic comparison of ASA.S1 confirmed that the isolated Acanthamoeba strain is closely related to genotype T13 supported by pairwise sequence identities of 97.1-98.0% and bootstrap support of 980 replicates with reference sequences of genotype T13. These results regarding the Acanthamoeba keratitis-causing isolate KaBo expands the number of known pathogenic genotypes to 12. To our knowledge, this is the first report of a T13 Acanthamoeba genotype being associated with keratitis in humans.
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