Evidence map›Paper›PMID 24802555›Full record

ArticleJournal of exposure science & environmental epidemiology2014

Improved exposure characterization with robotic (PIPER) sampling and association with children's respiratory symptoms, asthma and eczema.

Maya Ramagopal, Zuocheng Wang, Kathleen Black, Marta Hernandez, Adam A Stambler, Osiloke H Emoekpere, Gediminas Mainelis, Stuart L Shalat

Abstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Use of a Robotic Sampler (PIPER) for Evaluation of Particulate Matter Exposure and Eczema in Preschoolers.International journal of environmental research and public health · 2016
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maya RamagopalDepartment of Pediatrics, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Zuocheng WangDepartment of Environmental Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
Kathleen BlackEnvironmental and Occupational Health Sciences Institute, Piscataway, NJ, USA.
Marta HernandezEnvironmental and Occupational Health Sciences Institute, Piscataway, NJ, USA.
Adam A StamblerEnvironmental and Occupational Health Sciences Institute, Piscataway, NJ, USA.
Osiloke H EmoekpereEnvironmental and Occupational Health Sciences Institute, Piscataway, NJ, USA.
Gediminas Mainelis1] Department of Environmental Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA [2] Environmental and Occupational Health Sciences Institute, Piscataway, NJ, USA.
Stuart L Shalat1] Environmental and Occupational Health Sciences Institute, Piscataway, NJ, USA [2] Department of Environmental and Occupational Medicine, Rutgers-Robert Wood Johnson Medical School, Piscataway, NJ, USA.

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI ROBERT John LAUMBACH · 1988 to 2026
$47.4M
Validation of a Robotic Surrogate for Measurement of Early Childhood Personal ExpR01ES020415 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SHALAT, STUART LLOYD · 2011 to 2012
$895k
Characterization of Floor Level Aerosol (PM) Exposure and Childhood AsthmaR01ES014717 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SHALAT, STUART LLOYD · 2007 to 2009
$850k
NIEHS NIH HHS P30 ES005022NIEHS NIH HHS P30ES005022NIEHS NIH HHS R01 ES014717NIEHS NIH HHS R01ES014717NIEHS NIH HHS R01 ES020415NIEHS NIH HHS R01ES020415
6 · The paper itself

Abstract

Particulate matter (PM) and its constituents are recognized risk factors for the development of respiratory symptoms and illness in children. Most measurements of exposure have relied upon stationary indoor monitors (SIMs), overlooking the role of resuspended PM. To improve exposure characterization to resuspended aerosol PM, a recently developed methodology has been employed. The goal of this study was to characterize the resuspendable fraction of house dust and early childhood exposures to PM and its constituents in the child's home and compare conventional SIM and the Pre-toddler Inhalable Particulate Environmental Robotic (PIPER), an innovative mobile sampler. The study seeks to demonstrate that PIPER provides a more relevant estimate of exposure from inhalable particulate matter through improved correlation with respiratory symptoms in young children. Seventy-five households with children between 3 and 59 months of age were recruited from clinics in central New Jersey. Demographic information, and responses to a health questionnaire based upon that used by the International Study of Allergies and Asthma in Childhood (ISAAC), and household data were collected. Household exposures to inhalable PM (PM100) and endotoxin were determined with simultaneous SIM and mobile (PIPER) sampling. Univariate and multivariate analyses were carried out. History of wheeze ("recent" (<1 year) and "ever"), cough, asthma and eczema was evaluated. Multivariate analysis models included PM100 and endotoxin levels by tertiles of exposure. Risk of asthma for the highest tertile of PM100, as measured by PIPER (odds ratio=4.2; 95% confidence interval 0.7-24.0), was compared with measurements by SIM (odds ratio=0.7; 95% confidence interval 0.2-2.6). Measurements of PM and its constituents with PIPER are more strongly associated with asthma, eczema and wheeze compared with measurements using SIMs. Application of this methodology may provide useful insights into early childhood exposures related to the etiology of childhood illnesses associated with inhalation exposures.

Indexed as

Environmental ExposureRoboticsAsthmaChild, PreschoolEczemaEnvironmental MonitoringFemaleHumansInfantMaleParticulate MatterRespiratory SystemParticulate Matter

Identifiers

PMID24802555
PMCPMC4311520

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.