ReviewNature reviews. Microbiology2014
A re-evaluation of the archaeal membrane lipid biosynthetic pathway.
Review in Nature reviews. Microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed.
- Characterization of a CYP107 family vitamin DArchives of biochemistry and biophysics · 2026Article
- Anaerobic oxidation of methane supports a minimal microbial community in a subsurface biofilm at Ginsburg mud volcano.ISME communications · 2026Article
- Marine Cold Seep ANME-2/SRB Consortia Produce Their Lipid Biomass From Inorganic Carbon.Environmental microbiology · 2025Article
- Cyclization of archaeal membrane lipids impacts membrane protein activity and archaellum formation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Chemiosmotic ATP synthesis by minimal protocells.Cell reports. Physical science · 2025Article
- Discovering Hidden Archaeal and Bacterial Lipid Producers in a Euxinic Marine System.Environmental microbiology · 2025Article
- Cell envelope diversity and evolution across the bacterial tree of life.Nature microbiology · 2024Review
- The biosynthesis mechanism of bacterioruberin in halophilic archaea revealed by genome and transcriptome analysis.Applied and environmental microbiology · 2024Article
- Article
- The virome of the last eukaryotic common ancestor and eukaryogenesis.Nature microbiology · 2023Review
- Acid-tolerant bacteria and prospects in industrial and environmental applications.Applied microbiology and biotechnology · 2023Review
- Unexpected complexity of the ammonia monooxygenase in archaea.The ISME journal · 2023Article
- Alcohols as inhibitors of ammonia oxidizing archaea and bacteria.FEMS microbiology letters · 2023Article
- Membrane lipid and expression responses ofFrontiers in microbiology · 2023Article
- Lipidomic chemotaxonomy aligned with phylogeny of Halobacteria.Frontiers in microbiology · 2023Article
- Article
- The catalytic and structural basis of archaeal glycerophospholipid biosynthesis.Extremophiles : life under extreme conditions · 2022Review
- Highlighting the Unique Roles of RadicalJournal of bacteriology · 2022Review
- Catabolic protein degradation in marine sediments confined to distinct archaea.The ISME journal · 2022Article
- Functional Insights of Salinity Stress-Related Pathways in Metagenome-ResolvedApplied and environmental microbiology · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Archaea produce unique membrane lipids in which isoprenoid alkyl chains are bound to glycerol moieties via ether linkages. As cultured representatives of the Archaea have become increasingly available throughout the past decade, archaeal genomic and membrane lipid-composition data have also become available. In this Analysis article, we compare the amino acid sequences of the key enzymes of the archaeal ether-lipid biosynthesis pathway and critically evaluate past studies on the biochemical functions of these enzymes. We propose an alternative archaeal lipid biosynthetic pathway that is based on a 'multiple-key, multiple-lock' mechanism.
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Registered trials
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