Evidence map›Paper›PMID 24800249›Full record

ArticleBioMed research international2014

Meconium indicators of maternal alcohol abuse during pregnancy and association with patient characteristics.

Tamme W Goecke, Pascal Burger, Peter A Fasching, Abdulsallam Bakdash, Anne Engel, Lothar Häberle, Franziska Voigt, Florian Faschingbauer, Eva Raabe, Nicolai Maass and 4 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Tamme W GoeckeDepartment of Obstetrics and Gynecology, Friedrich-Alexander-University of Erlangen-Nuremberg, Universitaetsstraß 21-23, 91054 Erlangen, Germany ; Department of Obstetrics and Gynecology, University of RWTH Aachen, Pauwelsstrß 30, 52074 Aachen, Germany.
Pascal BurgerDepartment of Psychiatry and Psychotherapy, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6-10, 91054 Erlangen, Germany.
Peter A FaschingDepartment of Obstetrics and Gynecology, Friedrich-Alexander-University of Erlangen-Nuremberg, Universitaetsstraß 21-23, 91054 Erlangen, Germany.
Abdulsallam BakdashInstitute of Legal Medicine, University Hospital Charité, Hittorfstraße 18, 14195 Berlin, Germany.
Anne EngelDepartment of Obstetrics and Gynecology, Friedrich-Alexander-University of Erlangen-Nuremberg, Universitaetsstraß 21-23, 91054 Erlangen, Germany.
Lothar HäberleDepartment of Obstetrics and Gynecology, Friedrich-Alexander-University of Erlangen-Nuremberg, Universitaetsstraß 21-23, 91054 Erlangen, Germany.
Franziska VoigtDepartment of Obstetrics and Gynecology, Friedrich-Alexander-University of Erlangen-Nuremberg, Universitaetsstraß 21-23, 91054 Erlangen, Germany ; Department of Obstetrics and Gynecology, University of RWTH Aachen, Pauwelsstrß 30, 52074 Aachen, Germany.
Florian FaschingbauerDepartment of Obstetrics and Gynecology, Friedrich-Alexander-University of Erlangen-Nuremberg, Universitaetsstraß 21-23, 91054 Erlangen, Germany.
Eva RaabeDepartment of Obstetrics and Gynecology, Friedrich-Alexander-University of Erlangen-Nuremberg, Universitaetsstraß 21-23, 91054 Erlangen, Germany.
Nicolai MaassDepartment of Obstetrics and Gynecology, University of RWTH Aachen, Pauwelsstrß 30, 52074 Aachen, Germany.
Michael RotheLipidomix GmbH, Berliner Allee 261-269, 13088 Berlin, Germany.
Matthias W BeckmannDepartment of Obstetrics and Gynecology, Friedrich-Alexander-University of Erlangen-Nuremberg, Universitaetsstraß 21-23, 91054 Erlangen, Germany.
Fritz PragstInstitute of Legal Medicine, University Hospital Charité, Hittorfstraße 18, 14195 Berlin, Germany.
Johannes KornhuberDepartment of Psychiatry and Psychotherapy, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6-10, 91054 Erlangen, Germany.ORCID 0000-0002-8096-3987
Friedrich-Alexander-Universität Erlangen-Nürnberg · DECharité - Universitätsmedizin Berlin · DELipidomix (Germany) · DERWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimIdentification of women with moderate alcohol abuse during pregnancy is difficult. We correlated self-reported alcohol consumption during pregnancy and patient characteristics with objective alcohol indicators measured in fetal meconium.

methodsA total of 557 women singleton births and available psychological tests, obstetric data and meconium samples were included in statistical analysis. Alcohol metabolites (fatty acid ethyl esters (FAEEs) and ethyl glucuronide (EtG)), were determined from meconium and correlated with patient characteristics.

resultsWe found that 21.2% of the 557 participants admitted low-to-moderate alcohol consumption during pregnancy. Of the parameters analyzed from meconium, only EtG showed an association with alcohol history (P < 0.01). This association was inverse in cases with EtG value above 120 ng/g. These values indicate women with most severe alcohol consumption, who obviously denied having consumed alcohol during pregnancy. No other associations between socioeconomic or psychological characteristics and the drinking status (via meconium alcohol metabolites) could be found.

conclusionWomen who drink higher doses of ethanol during pregnancy, according to metabolite measures in meconium, might be less likely to admit alcohol consumption. No profile of socioeconomic or psychological characteristics of those women positively tested via meconium could be established.

Indexed as

AdultAlcoholismBirth WeightCohort StudiesFemaleGermanyHumansInfant, NewbornMaleMeconiumPregnancyPregnancy ComplicationsProspective StudiesPsychological TestsYoung Adult

Identifiers

PMID24800249
PMCPMC3985164
OpenAlexW2011290738

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.