Evidence map›Paper›PMID 24800226›Full record

ArticleBioMed research international2014

Applied graph-mining algorithms to study biomolecular interaction networks.

Ru Shen, Chittibabu Guda

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Open Data for Differential Network Analysis in Glioma.International journal of molecular sciences · 2020
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ru ShenDepartment of Computer Science, University at Albany, 1400 Washington Avenue, Albany, NY 12222, USA.ORCID 0000-0002-8363-0520
Chittibabu GudaDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, College of Medicine, Omaha, NE 68198-5145, USA ; Bioinformatics and Systems Biology Core, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-5393-9316
University at Albany, State University of New York · USUniversity of Nebraska Medical Center · US

Funding

Cataloging the subcellular and suborganellar proteomes of sequenced genomesR01GM086533 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI GUDA, CHITTIBABU · 2009 to 2013
$911k
NIGMS NIH HHS 1R01GM086533-01A1NIGMS NIH HHS R01 GM086533
6 · The paper itself

Abstract

Protein-protein interaction (PPI) networks carry vital information on the organization of molecular interactions in cellular systems. The identification of functionally relevant modules in PPI networks is one of the most important applications of biological network analysis. Computational analysis is becoming an indispensable tool to understand large-scale biomolecular interaction networks. Several types of computational methods have been developed and employed for the analysis of PPI networks. Of these computational methods, graph comparison and module detection are the two most commonly used strategies. This review summarizes current literature on graph kernel and graph alignment methods for graph comparison strategies, as well as module detection approaches including seed-and-extend, hierarchical clustering, optimization-based, probabilistic, and frequent subgraph methods. Herein, we provide a comprehensive review of the major algorithms employed under each theme, including our recently published frequent subgraph method, for detecting functional modules commonly shared across multiple cancer PPI networks.

Indexed as

AlgorithmsModels, BiologicalSignal TransductionAnimalsComputer SimulationData MiningHumansNeoplasm ProteinsNeoplasmsNumerical Analysis, Computer-AssistedProtein Interaction MappingNeoplasm Proteins

Identifiers

PMID24800226
PMCPMC3996886
OpenAlexW2082134159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.