ArticleSystems and synthetic biology2014
Identifying pseudogenes from hypothetical proteins for making synthetic proteins.
Article in Systems and synthetic biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Article
- Proteogenomic Approaches for Diseasome Studies.Methods in molecular biology (Clifton, N.J.) · 2025Review
- A novel gene from the acidophilic bacterium Leptospirillum sp. CF-1 and its role in oxidative stress and chromate tolerance.Biological research · 2022Article
- Hypothetical Proteins as Predecessors of Long Non-coding RNAs.Current genomics · 2020Review
- A model to predict the function of hypothetical proteins through a nine-point classification scoring schema.BMC bioinformatics · 2019Article
- On Brucella pathogenesis: looking for the unified challenge in systems and synthetic biology.Systems and synthetic biology · 2015Article
- In silico study of peptide inhibitors against BACE 1.Systems and synthetic biology · 2015Article
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Authors and funding
3 authors.
Funding
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Abstract
Nature selected certain regions of the genome for encoding proteins. Most of the sequences were used to encode only RNA. What happened to the remaining sections of the genome? It is possible that some sequences were retired and retained as non-functional entities called pseudogenes. Though several evolutionary prospects with functional endpoints exist, we looked at the possibility of hypothetical proteins correlating with the emergence of pseudogenes and potential of such genes to make novel synthetic molecules. In this commentary, we consider two key aspects: (1) does any correlation exist between hypothetical proteins and pseudogenes and (2)-can we make novel and functional proteins from pseudogenes?
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