Evidence map›Paper›PMID 24799937›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2014

The Effect of Mushroom Beta-Glucans from Solid Culture of Ganoderma lucidum on Inhibition of the Primary Tumor Metastasis.

Shiu-Nan Chen, Ching-Sheng Chang, Ming-Hsin Hung, Sherwin Chen, William Wang, Cheng-Jeng Tai, Chung-Lun Lu

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Frontiers in pharmacology · 2019
    Pooled it
  3. Review
  4. Article
  5. Fermentation WithFrontiers in nutrition · 2022
    Article
  6. Effects of Medicinal Fungi-Derived β-Glucan on Tumor Progression.Journal of fungi (Basel, Switzerland) · 2021
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Influence of Maitake (BioMed research international · 2020
    Article
  13. Article
  14. Potential of Mushroom Compounds as Immunomodulators in Cancer Immunotherapy: A Review.Evidence-based complementary and alternative medicine : eCAM · 2018
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shiu-Nan ChenCollege of Life Science, National Taiwan University, Section 4, Roosevelt Road, Taipei 10617, Taiwan.ORCID 0000-0002-8899-8404
Ching-Sheng ChangCollege of Life Science, National Taiwan University, Section 4, Roosevelt Road, Taipei 10617, Taiwan.ORCID 0000-0002-7485-0492
Ming-Hsin HungCollege of Life Science, National Taiwan University, Section 4, Roosevelt Road, Taipei 10617, Taiwan.
Sherwin ChenDepartment of Research and Development, Super Beta Glucan Inc., Irvine, CA, USA.
William WangDepartment of Research and Development, Super Beta Glucan Inc., Irvine, CA, USA.
Cheng-Jeng TaiDepartment of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan ; Division of Hematology and Oncology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 110, Taiwan.ORCID 0000-0001-9497-2414
Chung-Lun LuCollege of Life Science, National Taiwan University, Section 4, Roosevelt Road, Taipei 10617, Taiwan.
National Taiwan University · TWTaipei Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluates the effect of mushroom beta-glucans (MBGS) derived from solid culture of Ganoderma lucidum on tumor inhibition by examining size of the primary tumor and rate of metastasis in Lewis lung carcinoma (LLC) bearing mice (C57BL/6), given oral administration of MBGS with radiation therapy. A previous result showed that MBGS enhances NK cell-mediated cytotoxicity in mice without LLC bearing in advance. Furthermore, applications of MBGS in conjunction with radiation therapy were effective in controlling tumor growth, and rate of metastasis, life threatening, and can potentially serve as a protective factor for wounds and hair loss that resulted from the overgrowth of primary tumor in LLC bearing mice.

Identifiers

PMID24799937
PMCPMC3995106
OpenAlexW1965412651

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.