Evidence map›Paper›PMID 24799765›Full record

ArticleMediators of inflammation2014

Adipokines as potential biomarkers in rheumatoid arthritis.

Annalisa Del Prete, Valentina Salvi, Silvano Sozzani

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
  6. Review
  7. Chemerin is a key player in antimicrobial defense in skin.Cellular & molecular immunology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Organokines in Rheumatoid Arthritis: A Critical Review.International journal of molecular sciences · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Annalisa Del PreteDepartment of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy ; Humanitas Clinical and Research Center, via Manzoni 113, 20089 Rozzano, Italy.
Valentina SalviDepartment of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Silvano SozzaniDepartment of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy ; Humanitas Clinical and Research Center, via Manzoni 113, 20089 Rozzano, Italy.
University of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic systemic inflammatory autoimmune disease characterized by severe joint injury. Recently, research has been focusing on the possible identification of predictor markers of disease onset and/or progression, of joint damage, and of therapeutic response. Recent findings have uncovered the role of white adipose tissue as a pleiotropic organ not only specialized in endocrine functions but also able to control multiple physiopathological processes, including inflammation. Adipokines are a family of soluble mediators secreted by white adipose tissue endowed with a wide spectrum of actions. This review will focus on the recent advances on the role of the adipokine network in the pathogenesis of RA. A particular attention will be devoted to the action of these proteins on RA effector cells, and on the possibility to use circulating levels of adipokines as potential biomarkers of disease activity and therapeutic response.

Indexed as

AdipokinesArthritis, RheumatoidBiomarkersCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell LineChemokine CCL5FinasterideFlow CytometryHumansImmunohistochemistryMalePolymerase Chain ReactionProstateAdipokinesBiomarkersChemokine CCL5Finasteride

Identifiers

PMID24799765
PMCPMC3985296
OpenAlexW2058694236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.