Evidence map›Paper›PMID 24799739›Full record

ArticleIndian journal of pharmaceutical sciences2014

Evaluation of nanodispersion of iron oxides using various polymers.

Y Tanaka, H Ueyama, M Ogata, T Daikoku, M Morimoto, A Kitagawa, Y Imajo, T Tahara, M Inkyo, N Yamaguchi and 1 more

Abstract read
In one paragraph

Article in Indian journal of pharmaceutical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Y TanakaLaboratory of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hiro-koshingai, Kure, Hiroshima 7370112, Japan.
H UeyamaLaboratory of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hiro-koshingai, Kure, Hiroshima 7370112, Japan.
M OgataLaboratory of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hiro-koshingai, Kure, Hiroshima 7370112, Japan.
T DaikokuLaboratory of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hiro-koshingai, Kure, Hiroshima 7370112, Japan.
M MorimotoLaboratory of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hiro-koshingai, Kure, Hiroshima 7370112, Japan.
A KitagawaKotobuki Industries Co., Ltd., Ohashi-Gyoen-Bldg. 2F, 1-8-1 Shinjuku, Shinjuku-ku, Tokyo 1600022, Japan.
Y ImajoKotobuki Industries Co., Ltd., Ohashi-Gyoen-Bldg. 2F, 1-8-1 Shinjuku, Shinjuku-ku, Tokyo 1600022, Japan.
T TaharaKotobuki Industries Co., Ltd., Ohashi-Gyoen-Bldg. 2F, 1-8-1 Shinjuku, Shinjuku-ku, Tokyo 1600022, Japan.
M InkyoKotobuki Industries Co., Ltd., Ohashi-Gyoen-Bldg. 2F, 1-8-1 Shinjuku, Shinjuku-ku, Tokyo 1600022, Japan.
N YamaguchiKishi Kasei Co., Ltd., 1-11-22 Fukuura, Kanazawa-ku, Yokohama, Kanagawa 2360004, Japan.
S NagataLaboratory of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hiro-koshingai, Kure, Hiroshima 7370112, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to create Fe2O3 and Fe2O3·H2O nanoparticles, various polymers were used as dispersing agents, and the resulting effects on the dispersibility and nanoparticulation of the iron oxides were evaluated. It was revealed that not only the solution viscosity but also the molecular length of the polymers and the surface tension of the particles affected the dispersibility of Fe2O3 and Fe2O3·H2O particles. Using the dispersing agents 7.5% hydroxypropylcellulose-SSL, 6.0% Pharmacoat 603, 5.0% and 6.5% Pharmacoat 904 and 7.0% Metolose SM-4, Fe2O3 nanoparticles were successfully fabricated by wet milling using Ultra Apex Mill. Fe2O3·H2O nanoparticles could also be produced using 5.0% hydroxypropylcellulose-SSL and 4.0 and 7.0% Pharmacoat 904. The index for dispersibility developed in this study appears to be an effective indicator of success in fabricating nanoparticles of iron oxides by wet milling using Ultra Apex Mill.

Indexed as

Dispersibilityiron oxidenanoparticlepolymerwet-milling

Identifiers

PMID24799739
PMCPMC4007256

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.