ArticleProceedings of the National Academy of Sciences of the United States of America2014
Phyllotreta striolata flea beetles use host plant defense compounds to create their own glucosinolate-myrosinase system.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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57 citing papers in PubMed, 127 citations in OpenAlex.
- Genetic Variation in Chemical Defence Affects Protection of an Herbivorous Insect Against Predation.Molecular ecology · 2026Article
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- Glucosinolate hydrolysis products suppress entomopathogenic nematodes in vitro but do not protect sequestering flea beetle larvae in vivo.Pest management science · 2026Article
- Comparative Control ofInsects · 2025Article
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- Molecular evolution of dietary shifts in ladybird beetles (Coleoptera: Coccinellidae): from fungivory to carnivory and herbivory.BMC biology · 2025Article
- Effects of Postharvest SOPlants (Basel, Switzerland) · 2024Article
- Aphid Resistance Segregates Independently of Cardenolide and Glucosinolate Content in anPlants (Basel, Switzerland) · 2024Article
- Aphid resistance segregates independently of cardiac glycoside and glucosinolate content in anbioRxiv : the preprint server for biology · 2024Article
- Seed treatment with clothianidin induces changes in plant metabolism and alters pollinator foraging preferences.Ecotoxicology (London, England) · 2023Article
- Metabolism of plant-derived toxins from its insect host increases the success of the entomopathogenic fungus Beauveria bassiana.The ISME journal · 2023Article
- Screening of Fungal Strains and Formulations ofInsects · 2023Article
- Perspectives for integrated insect pest protection in oilseed rape breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Review
- Family dinner: Transcriptional plasticity of five Noctuidae (Lepidoptera) feeding on three host plant species.Ecology and evolution · 2022Article
- The Evolution of Glycoside Hydrolase Family 1 in Insects Related to Their Adaptation to Plant Utilization.Insects · 2022Article
- Unique metabolism of different glucosinolates in larvae and adults of a leaf beetle specialised on Brassicaceae.Scientific reports · 2022Article
- Molecular Cloning, Expression and Characterisation of a Bacterial Myrosinase from Citrobacter Wye1.The protein journal · 2022Article
- The Cellular and Subcellular Organization of the Glucosinolate-Myrosinase System against Herbivores and Pathogens.International journal of molecular sciences · 2022Review
- An inducible gene from glycoside hydrolase one family ofFrontiers in physiology · 2022Article
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Authors and funding
15 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability of a specialized herbivore to overcome the chemical defense of a particular plant taxon not only makes it accessible as a food source but may also provide metabolites to be exploited for communication or chemical defense. Phyllotreta flea beetles are adapted to crucifer plants (Brassicales) that are defended by the glucosinolate-myrosinase system, the so-called "mustard-oil bomb." Tissue damage caused by insect feeding brings glucosinolates into contact with the plant enzyme myrosinase, which hydrolyzes them to form toxic compounds, such as isothiocyanates. However, we previously observed that Phyllotreta striolata beetles themselves produce volatile glucosinolate hydrolysis products. Here, we show that P. striolata adults selectively accumulate glucosinolates from their food plants to up to 1.75% of their body weight and express their own myrosinase. By combining proteomics and transcriptomics, a gene responsible for myrosinase activity in P. striolata was identified. The major substrates of the heterologously expressed myrosinase were aliphatic glucosinolates, which were hydrolyzed with at least fourfold higher efficiency than aromatic and indolic glucosinolates, and β-O-glucosides. The identified beetle myrosinase belongs to the glycoside hydrolase family 1 and has up to 76% sequence similarity to other β-glucosidases. Phylogenetic analyses suggest species-specific diversification of this gene family in insects and an independent evolution of the beetle myrosinase from other insect β-glucosidases.
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