ArticleJournal of developmental and behavioral pediatrics : JDBP2014
Intervention for optimal outcome in children and adolescents with a history of autism.
Article in Journal of developmental and behavioral pediatrics : JDBP, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 4 syntheses or guidelines pooled it, 195 citations in OpenAlex.
- Narrative systematic review for autism spectrum disorders screening tools in school settings.BMJ open · 2026Pooled it
- How has DSM-5 Affected Autism Diagnosis? A 5-Year Follow-Up Systematic Literature Review and Meta-analysis.Journal of autism and developmental disorders · 2020Pooled it
- A systematic review and meta-analysis of comprehensive interventions for pre-school children with autism spectrum disorder (ASD).PloS one · 2017Pooled it
- The Effects of DSM-5 Criteria on Number of Individuals Diagnosed with Autism Spectrum Disorder: A Systematic Review.Journal of autism and developmental disorders · 2015Pooled it
- Secondary effects of dialectical behaviour therapy on social functioning, quality of life, and autism traits in autistic adults with suicidality.Autism : the international journal of research and practice · 2025Trial
- Trial
- Factors Associated with Extreme Waiting Times for Child Developmental Diagnostic Assessments: A Mixed-Methods Service Evaluation in Sydney.Children (Basel, Switzerland) · 2026Article
- Rationale and Methods for the Prospective Genetic Risk Evaluation and Assessment (PROGRESS) in Autism Center at Columbia University.Pediatric research · 2026Article
- Machine learning-based prediction of intellectual disability in children with autism spectrum disorder: using behavioral observation techniques.BMC psychiatry · 2026Article
- Progress and opportunity in developmental neurobiology and youth mental health.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Association of maternal endometriosis with autism spectrum disorder in offspring: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- The Influence of Policy on Early Diagnosis and Other Autism Services: A Narrative Review.Review journal of autism and developmental disorders · 2025Article
- Cognitive Development in Children with Autism Spectrum Disorder and the Moderating Role of Intervention and ASD Persistence.Behavioral sciences (Basel, Switzerland) · 2025Article
- Sexual Health Education for Autistic Adolescents in the Arab World: Can Culturally Sensitive Behavioural Activation Help with Inappropriate Sexual Behaviour?Journal of autism and developmental disorders · 2025Article
- Developmental Assessment in Children at Higher Likelihood for Developmental Delays - Comparison of Parent Report and Direct Assessment.Journal of autism and developmental disorders · 2025Article
- Neurodiversity: A Behavior Analyst's Perspective.Perspectives on behavior science · 2025Article
- Advocacy and Open Science in the UK: Case Studies in the Autism Wars.Behavior analysis in practice · 2025Article
- Clinician-caregiver informant discrepancy is associated with sex, diagnosis age, and intervention use among autistic children.Autism : the international journal of research and practice · 2025Article
- Parent-Led Applied Behavior Analysis to Impact Clinical Outcomes for Individuals on the Autism Spectrum: Retrospective Chart Review.JMIR pediatrics and parenting · 2024Article
- Autism and cerebral palsy: evidence for converging phenotypes.Pediatric research · 2024Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
objectiveAutism spectrum disorders (ASDs) were once considered lifelong disorders, but recent findings indicate that some children with ASDs no longer meet diagnostic criteria for any ASD and reach normal cognitive function. These children are considered to have achieved "optimal outcomes" (OO). The present study aimed to retrospectively examine group differences in the intervention history of children and adolescents with OO and those with high-functioning autism (HFA).
methodThe current study examined intervention histories in 25 individuals with OO and 34 individuals with HFA (current age, 8-21 years), who did not differ on age, sex, nonverbal intelligence, or family income. Intervention history was collected through detailed parent questionnaires.
resultsChildren in the OO group had earlier parental concern, received earlier referrals to specialists, and had earlier and more intensive intervention than those in the HFA group. Substantially more children with OO than HFA received applied behavior analysis (ABA) therapy, although for children who received ABA, the intensity did not differ between the groups. Children in the HFA group were more likely to have received medication, especially antipsychotics and antidepressants. There were no group differences in the percent of children receiving special diets or supplements.
conclusionThese data suggest that OO individuals generally receive earlier, more intense interventions, and more ABA, whereas HFA individuals receive more pharmacologic treatments. Although the use of retrospective data is a clear limitation to the current study, the substantial differences in the reported provision of early intervention, and ABA in particular, is highly suggestive and should be replicated in prospective studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.