ReviewCurrent opinion in cell biology2014
Drosophila blood cell chemotaxis.
Review in Current opinion in cell biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 40 citations in OpenAlex.
- Cdc42 and Rac2 act through the formin-like Frl/FMNL to control lamellocyte shape and encapsulation of parasitoid wasp eggs in Drosophila.PLoS pathogens · 2026Article
- Roles of efferocytosis in wound repair: Process, cells, and signals.Genes & diseases · 2026Review
- Characterization of Anopheles gambiae immune cells through genetic and functional immunophenotyping.Nature communications · 2025Article
- Drosophila complement-like Mcr acts as a wound-induced inflammatory chemoattractant.Current biology : CB · 2025Article
- Exploring new dimensions of immune cell biology inbioRxiv : the preprint server for biology · 2024Article
- Single-cell transcriptomics identifies new blood cell populations in Drosophila released at the onset of metamorphosis.Development (Cambridge, England) · 2023Article
- Hematopoietic plasticity mapped ineLife · 2022Review
- p53 Related Protein Kinase is Required for Arp2/3-Dependent Actin Dynamics of Hemocytes inFrontiers in cell and developmental biology · 2022Article
- Comparative RNA-Seq analyses of Drosophila plasmatocytes reveal gene specific signatures in response to clean injury and septic injury.PloS one · 2020Article
- Chemotaxis Assay forFrontiers in cell and developmental biology · 2020Article
- Concepts of GPCR-controlled navigation in the immune system.Immunological reviews · 2019Review
- A tissue communication network coordinating innate immune response during muscle stress.Journal of cell science · 2018Article
- Hedgehog signaling from the Posterior Signaling Center maintains U-shaped expression and a prohemocyte population in Drosophila.Developmental biology · 2018Article
- Cell motility in cancer invasion and metastasis: insights from simple model organisms.Nature reviews. Cancer · 2018Review
- Echinochrome A Release by Red Spherule Cells Is an Iron-Withholding Strategy of Sea Urchin Innate Immunity.Journal of innate immunity · 2018Article
- Mosquito Hemocytes Associate With Circulatory Structures That Support Intracardiac Retrograde Hemolymph Flow.Frontiers in physiology · 2018Article
- Article
- Ena/VASP proteins regulate activated T-cell trafficking by promoting diapedesis during transendothelial migration.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Macrophage Functions in Tissue Patterning and Disease: New Insights from the Fly.Developmental cell · 2017Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Drosophila melanogaster contains a population of blood cells called hemocytes that represent the functional equivalent of vertebrate macrophages. These cells undergo directed migrations to disperse during development and reach sites of tissue damage or altered self. These chemotactic behaviors are controlled by the expression of PDGF/Vegf-related ligands in developing embryos and local production of hydrogen peroxide at wounds. Recent work reveals that many molecules important in vertebrate cell motility, including integrins, formins, Ena/VASP proteins and the SCAR/WAVE complex, have a conserved function in these innate immune cells. The use of this model organism has elucidated how damage signals are activated by calcium signaling during inflammation and that the steroid hormone ecdysone activates immune competence at key developmental stages.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.