ArticleAmerican journal of human biology : the official journal of the Human Biology Council
Prevalence of adiposity and associated cardiometabolic risk factors in the Samoan genome-wide association study.
Article in American journal of human biology : the official journal of the Human Biology Council. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 4 of them syntheses that pooled it.
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Who cites it
62 citing papers in PubMed, 4 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Type 2 Diabetes Prevalence, Control and Management within Fiji,Kiribati, Samoa, the Solomon Islands, Tonga, and Vanuatu: A ScopingReview with a Systematic Approach.Current diabetes reviews · 2024Pooled it
- Type 2 Diabetes Prevalence, Control and Management within Fiji,Kiribati, Samoa, the Solomon Islands, Tonga, and Vanuatu: A ScopingReview with a Systematic Approach.Current diabetes reviews · 2024Pooled it
- Association of rs9939609 in FTO with BMI among Polynesian peoples living in Aotearoa New Zealand and other Pacific nations.Journal of human genetics · 2023Pooled it
- A stop-gain variant inHGG advances · 2023Pooled it
- The Soifua Manuia reference panel with 2,570 Samoan haplotypes improves genotype imputation quality among Samoans.Communications biology · 2026Article
- Structural Variant Imputation in Samoans Using a Population-Specific Reference Panel.medRxiv : the preprint server for health sciences · 2026Article
- Meta-analysis of over 8,000 individuals from Hawai'i and Samoa for genetic associations to cardiometabolic phenotypes.medRxiv : the preprint server for health sciences · 2026Article
- Reproductive and metabolic hormone associations in adult Samoan males with and without obesity.Evolution, medicine, and public health · 2026Article
- Article
- Serum anti-mullerian hormone levels and age among Samoan women.Reproductive biology and endocrinology : RB&E · 2025Article
- Advantage in Aging Cognition Associated with theGeroPsych · 2024Article
- Characterization of sleep apnea among a sample of adults from Samoa.Sleep epidemiology · 2024Article
- Indication of mixed glucose and fatty acid use by inferred brown adipose tissue activity in Samoans.American journal of human biology : the official journal of the Human Biology Council · 2024Article
- When the cold gets under your skin: Evidence for brown adipose tissue activity in Samoan adults.American journal of biological anthropology · 2024Article
- Article
- Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort.PloS one · 2024Article
- Compound heterozygous splicing variants expand the genotypic spectrum of EMC1-related disorders.Clinical genetics · 2023Article
- Validity of anthropometric equation-based estimators of fat mass in Samoan adults.American journal of human biology : the official journal of the Human Biology Council · 2023Article
- Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries.Genetic epidemiology · 2023Article
- Consensus-building during the Becoming Breastfeeding Friendly (BBF) initiative in Samoa: A qualitative content analysis.PLOS global public health · 2023Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
objectiveTo describe the prevalence of obesity-related noncommunicable diseases (NCDs) and associated risk factors in a sample of Samoan adults studied in 2010 as part of a genome-wide assocation study (GWAS) for obesity related traits.
methodsAnthropometric and biochemical data collected from n = 3,475 participants (n = 1,437 male; n = 2,038 female) aged 24.5 to <65 years were used to describe the prevalence of obesity, diabetes, hypertension, and dyslipidemia within the study sample. One way analysis of variance, χ(2) tests, and binary logistic regression were used to identify differences in disease and risk factor prevalence by 10-year age group, gender, or by census region of residence.
resultsObesity was highly prevalent among the study sample; 64.6% of females and 41.2% of males were obese according to Polynesian cutoffs (BMI ≥ 32 kg/m(2) ). Females were less likely than males to have hypertension (31.7% vs. 36.7%) but equally likely to have diabetes (17.8% vs. 16.4%). With the exception of obesity and low HDL-cholesterol in females only, there were significant differences in the prevalence of all NCDs and associated risk factors by age group, with the oldest age group (55 to <65 years) most affected. In both sexes, residents of the Apia Urban Area were at significantly greater risk of obesity, diabetes, low HDL-cholesterol, and high triglycerides than residents of the more rural Savaii region.
conclusionsThe phenotypic characteristics of this sample provide evidence of a continuation of previously reported temporal trends toward obesity and its associated disorders. Attention must be paid to the critical NCD situation in Samoa.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.