Evidence map›Paper›PMID 24799088›Full record

ReviewJournal of cellular physiology2014

Big data bioinformatics.

Casey S Greene, Jie Tan, Matthew Ung, Jason H Moore, Chao Cheng

Erratum issuedAbstract readReview
In one paragraph

Review in Journal of cellular physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Multi-omics and bulk sequencing analyses reveal the roles of prognosis and immune aspects of super-enhancer-induced ZBED2 in pan-cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  3. Article
  4. Artificial intelligence in bioinformatics: a survey.Briefings in bioinformatics · 2025
    Review
  5. Article
  6. Review
  7. PmiR-SelectMolecular genetics and genomics : MGG · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. FAIR privacy-preserving operation of large genomic variant calling format (VCF) data without download or installation.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024
    Article
  13. Review
  14. Recent Advances in DNA Nanomaterials.Nanomaterials (Basel, Switzerland) · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Casey S GreeneDepartment of Genetics, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; Institute for Quantitative Biomedical Sciences, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire; Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.
Jie Tan
Matthew Ung
Jason H Moore
Chao Cheng

Funding

Quantitative Biology Research InstituteP20GM103534 · NIGMS · DARTMOUTH COLLEGE · PI AMOS, CHRISTOPHER I. · 2012 to 2016
$8.6M
Bioinformatics Strategies for Genome-Wide Association StudiesR01LM010098 · NLM · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H., WILLIAMS, SCOTT MATTHEW · 2009 to 2023
$5.1M
Bioinformatics Strategies: Biodefense Vaccine ResearchR01AI059694 · NIAID · DARTMOUTH COLLEGE · PI MOORE, JASON H. · 2004 to 2012
$4.5M
Machine Learning Prediction of Cancer SusceptibilityR01LM009012 · NLM · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H. · 2006 to 2014
$3.3M
Bioinformatics Approaches to Visual Disease GeneticsR01EY022300 · NEI · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H. · 2012 to 2014
$947k
NEI NIH HHS EY022300NEI NIH HHS R01 EY022300NIAID NIH HHS AI59694NIAID NIH HHS R01 AI059694NIGMS NIH HHS GM103534NIGMS NIH HHS P20 GM103534NLM NIH HHS LM009012NLM NIH HHS LM010098NLM NIH HHS R01 LM009012NLM NIH HHS R01 LM010098
6 · The paper itself

Abstract

Recent technological advances allow for high throughput profiling of biological systems in a cost-efficient manner. The low cost of data generation is leading us to the "big data" era. The availability of big data provides unprecedented opportunities but also raises new challenges for data mining and analysis. In this review, we introduce key concepts in the analysis of big data, including both "machine learning" algorithms as well as "unsupervised" and "supervised" examples of each. We note packages for the R programming language that are available to perform machine learning analyses. In addition to programming based solutions, we review webservers that allow users with limited or no programming background to perform these analyses on large data compendia.

Indexed as

SoftwareArtificial IntelligenceComputational BiologyData MiningGene Expression ProfilingHigh-Throughput Screening AssaysHumans

Identifiers

PMID24799088
PMCPMC5604462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.