Evidence map›Paper›PMID 24797797›Full record

Trial reportPloS one2014

Effects of intermittent training on anaerobic performance and MCT transporters in athletes.

Grégoire Millet, David J Bentley, Belle Roels, Lars R Mc Naughton, Jacques Mercier, David Cameron-Smith

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Test-retest variability of VOScandinavian journal of medicine & science in sports · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Grégoire MilletISSUL Institute of Sport Sciences University of Lausanne, Lausanne, Switzerland; Department of Physiology, University of Lausanne, Lausanne, Switzerland.
David J BentleyFaculty of Health Science, University of Adelaide, Adelaide, South Australia, Australia.
Belle RoelsORION, Clinical Services Ltd, London, England.
Lars R Mc NaughtonDepartment of Sport and Physical Activity, Edge Hill University, Ormskirk, Lancashire, England.
Jacques MercierLaboratoire de physiologie des Interactions EA 701, Institut de Biologie, Montpellier, France.
David Cameron-SmithSchool of Nutrition and Exercise Sciences, Deakin University, Melbourne, Victoria, Australia; Liggins Institute, University of Auckland, Auckland, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined the effects of intermittent hypoxic training (IHT) on skeletal muscle monocarboxylate lactate transporter (MCT) expression and anaerobic performance in trained athletes. Cyclists were assigned to two interventions, either normoxic (N; n = 8; 150 mmHg PIO2) or hypoxic (H; n = 10; ∼3000 m, 100 mmHg PIO2) over a three week training (5×1 h-1h30 x week(-1)) period. Prior to and after training, an incremental exercise test to exhaustion (EXT) was performed in normoxia together with a 2 min time trial (TT). Biopsy samples from the vastus lateralis were analyzed for MCT1 and MCT4 using immuno-blotting techniques. The peak power output (PPO) increased (p<0.05) after training (7.2% and 6.6% for N and H, respectively), but VO2max showed no significant change. The average power output in the TT improved significantly (7.3% and 6.4% for N and H, respectively). No differences were found in MCT1 and MCT4 protein content, before and after the training in either the N or H group. These results indicate there are no additional benefits of IHT when compared to similar normoxic training. Hence, the addition of the hypoxic stimulus on anaerobic performance or MCT expression after a three-week training period is ineffective.

Indexed as

AthletesAdultAnaerobic ThresholdExerciseGene Expression RegulationHumansMaleMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersMuscle ProteinsMuscle, SkeletalPhysical FitnessSymportersMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersMuscle ProteinsSLC16A4 protein, humanSymporters

Identifiers

PMID24797797
PMCPMC4010422

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.