Evidence map›Paper›PMID 24797638›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2014

A comparison of Progrip(®) and Adhesix (®) self-adhering hernia meshes in an onlay model in the rat.

S Gruber-Blum, N Riepl, J Brand, C Keibl, H Redl, R H Fortelny, A H Petter-Puchner

Abstract readComparative StudyEvaluation Study
PubMed Publisher
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  3. Review
  4. Medial incisional ventral hernia repair with AdhesixHernia : the journal of hernias and abdominal wall surgery · 2023
    Article
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  6. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

S Gruber-BlumLudwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstrasse 13, Austrian Cluster for Tissue Regeneration, 1200, Vienna, Austria.
N Riepl
J Brand
C Keibl
H Redl
R H Fortelny
A H Petter-Puchner
Ludwig Boltzmann Institute for Experimental and Clinical Traumatology · ATAustrian Cluster for Tissue Regeneration · ATParacelsus Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtraumatic fixation is a key element of modern hernia repair. Two different concepts of self-adhering meshes were directly compared in this study. Adhesix(®) (AH) is coated with polyethylene glycol (PEG) and polyvinylpyrrolidone (PVP), whereas Parietene Progrip(®) (PP) relies on the mechanical principle of micro grips made of polylactic acid (PLA). These meshes are the main competitors in the field.

methodsAH and PP were tested in Sprague-Dawley rats at 14 and 90 days. Four groups were operated (n = 8 animals per group). Two meshes were implanted per animal in an operation model of onlay hernia repair. Dislocation, tissue integration and foreign-body reaction were evaluated.

resultsAH dislocated significantly more frequently (every second mesh) at both time points of observation than PP. Tissue integration was good with PP and could not be reliably assessed in AH due to frequent dislocation. Histologic examination revealed only a mild foreign body reaction in all groups.

conclusionsIn our hands, PP (mechanical grip fixation) was superior to hydrogel fixation with PEG and PVP in AH in an onlay model. The reason for dislocation of AH requires further clarification as well as the impact of long-term degradation of the PLA grips.

Indexed as

Surgical MeshAnimalsBiocompatible MaterialsDisease Models, AnimalForeign-Body MigrationForeign-Body ReactionHerniorrhaphyMaleProstheses and ImplantsProsthesis FailureRatsRats, Sprague-DawleyWound HealingBiocompatible Materials

Identifiers

PMID24797638
OpenAlexW1971211306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.