Evidence map›Paper›PMID 24797222›Full record

Trial reportJournal of clinical periodontology2014

The effect of periodontal therapy on glycaemic control in a Hispanic population with type 2 diabetes: a randomized controlled trial.

Isabel C Gay, Duong T Tran, Adriana C Cavender, Robin Weltman, Jennifer Chang, Estelle Luckenbach, Gena D Tribble

Registry-linked trialOpen access · greenAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of clinical periodontology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01128374 (The Effect of Non-Surgical Periodontal Therapy on Glycemic Control and Bacterial Levels in a Mexican-American Population With Type 2 DiabetesS), which is not on this map. Cited by 18 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 7 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01128374 nacompletednot on this map

The Effect of Non-Surgical Periodontal Therapy on Glycemic Control and Bacterial Levels in a Mexican-American Population With Type 2 DiabetesS

TypeinterventionalSponsorThe University of Texas Health Science Center, HoustonRan2010 to 2012Enrolled134ConditionsType 2 Diabetes Mellitus, Periodontal DiseaseArmsPeriodontal Scaling and root planing
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 7 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  8. Trial
  9. Review
  10. Review
  11. Article
  12. Metabolic syndrome and periodontal disease: An overview for physicians.Journal of family medicine and primary care · 2019
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Periodontal status among patients with diabetes in Nuuk, Greenland.International journal of circumpolar health · 2014
    Observational
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Isabel C GayDental School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Duong T Tran
Adriana C Cavender
Robin Weltman
Jennifer Chang
Estelle Luckenbach
Gena D Tribble
The University of Texas Health Science Center at Houston · USMenninger Clinic · US

Funding

U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
CTSA: K12 COMPONENTKL2RR024149 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2011
$6.7M
NCATS NIH HHS UL1 TR000371NCRR NIH HHS KL2 RR024149NCRR NIH HHS UL1 RR024148
6 · The paper itself

Abstract

objectiveIn the Mexican-American population, the prevalence of Type 2 diabetes mellitus (T2DM) is as high as 50% of the population. This randomized controlled clinical trial was designed to elucidate how treatment of periodontal disease affects HbA1c values in this population. MATERIALS AND

methodsOne hundred and fifty-four T2DM patients with periodontal disease were enrolled in the study. The test group was treated with scaling and root planing (SRP); the control group received oral hygiene instructions. At baseline and 4-6 weeks after therapy, a complete periodontal examination was performed. Blood was collected at baseline and 4 months later for HbA1c levels.

resultsOne hundred and twenty-six individuals completed the study. Baseline mean ± SD HbA1c for the test and control groups were 9.0 ± 2.3% and 8.4 ± 2.0% respectively. Non-significant difference in HbA1c reductions (0.6 ± 2.1% and 0.3 ± 1.7%) was found between test and control groups at 4 months. Comparisons of the periodontal clinical parameters between the test and control groups found significant differences with improved results in the test subjects.

conclusionsNo statistically significant differences were found in the changes of HbA1c levels between test and control groups. Non-surgical periodontal therapy improved the magnitude of change in periodontal parameters as compared to the control subjects. ClinicalTrials.gov Identifier: NCT01128374.

Indexed as

Hispanic or LatinoChronic PeriodontitisDental Devices, Home CareDental ScalingDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGingival RecessionGlycated HemoglobinHumansMaleMiddle AgedOral HygienePeriodontal Attachment LossPeriodontal PocketRoot PlaningGlycated HemoglobinHbA1cHispanic populationperiodontitisscaling and root planingtype 2 diabetes mellitus

Identifiers

PMID24797222
PMCPMC4080623
OpenAlexW2088556092

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.