Evidence map›Paper›PMID 24797172›Full record

ReviewMedicine2014

Rosai-Dorfman disease of the central nervous system: report of 6 cases and review of the literature.

Jose D Sandoval-Sus, Ana C Sandoval-Leon, Jennifer R Chapman, Jose Velazquez-Vega, Maria J Borja, Shai Rosenberg, Alexander Lossos, Izidore S Lossos

Abstract readCase ReportsReview
In one paragraph

Review in Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  5. Article
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  12. Approach to the Patient: From Endocrinopathy to the Diagnosis of a Histiocytic Disorder.The Journal of clinical endocrinology and metabolism · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Recurrent Soft Tissue Rosai Dorfman Disease of Right Medial Thigh Lipoma With Lymph Node Involvement.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024
    Article
  20. Rosai-Dorfman disease of the cauda equina: illustrative case.Journal of neurosurgery. Case lessons · 2024
    Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jose D Sandoval-SusFrom the Department of Medicine (JDS-S, ACS-L, ISL), Department of Pathology (JRC, JV-V), and Department of Radiology (MJB), University of Miami, Miami, Florida, Division of Hematology-Oncology (ISL), Department of Medicine, and Department of Molecular and Cellular Pharmacology (ISL), University of Miami, Sylvester Comprehensive Cancer Center, Miami, Florida, and Department of Neurology (SR, AL), Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Ana C Sandoval-Leon
Jennifer R Chapman
Jose Velazquez-Vega
Maria J Borja
Shai Rosenberg
Alexander Lossos
Izidore S Lossos

Funding

Significance and Function of HGAL in LymphomaR01CA109335 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LOSSOS, IZIDORE S · 2005 to 2013
$2.1M
NCI NIH HHS CA109335NCI NIH HHS R01 CA109335
6 · The paper itself

Abstract

Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy (SHML), is an uncommon benign idiopathic lymphoproliferative disorder. The histologic hallmark of RDD is the finding of emperipolesis displayed by lesional histiocytes. While RDD most commonly affects lymph nodes, extranodal involvement of multiple organs has been reported, including the central nervous system (CNS). However, CNS involvement in RDD is rare and is not well characterized. As a result, therapeutic approaches to CNS involvement in RDD are not well established. Herein we report 6 cases of RDD with isolated CNS involvement and review the literature on RDD with CNS involvement. One of the presented cases exhibited intramedullary involvement of the spinal cord--a very rare form of RDD with CNS involvement.

Indexed as

AdultCentral Nervous System DiseasesDiagnosis, DifferentialFemaleHistiocytosis, SinusHumansMaleMiddle Aged

Identifiers

PMID24797172
PMCPMC4632912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.