ArticleNature communications2014
On-the-fly decoding luminescence lifetimes in the microsecond region for lanthanide-encoded suspension arrays.
Article in Nature communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 165 citations in OpenAlex.
- Harnessing Rare-Earth Materials as Exogenous Contrast Agents for Enhanced Photoacoustic Imaging.Chemical & biomedical imaging · 2026Review
- Lifetime Manipulation by Excitation Power in Lanthanide Core-Shell Nanocrystals Without Altering Composition.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Review
- Fluorescence Lifetime Measurements and Analyses: Protocols Using Flow Cytometry and High-Throughput Microscopy.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Low-rate smartphone videoscopy for microsecond luminescence lifetime imaging with machine learning.PNAS nexus · 2023Article
- Photoluminescent Polymer Aerogels with R, G and B Emission.International journal of molecular sciences · 2022Article
- Optical Absorption on Electron Quantum-Confined States of Perovskite Quantum Dots.Nanomaterials (Basel, Switzerland) · 2022Article
- Review
- Development of Novel Therapeutics Targeting the Blood-Brain Barrier: From Barrier to Carrier.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- The Use of Upconversion Nanoparticles in Prostate Cancer Photodynamic Therapy.Life (Basel, Switzerland) · 2021Review
- Lifetime-Engineered Carbon Nanodots for Time Division Duplexing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Experimental validation of a modeling framework for upconversion enhancement in 1D-photonic crystals.Nature communications · 2021Article
- Real-Time Imaging of Short-Wave Infrared Luminescence Lifetimes for Anti-counterfeiting Applications.Frontiers in chemistry · 2021Article
- Lanthanide-Based Optical Probes of Biological Systems.Cell chemical biology · 2020Review
- Manipulating the fluorescence lifetime at the sub-cellular scale via photo-switchable barcoding.Nature communications · 2020Article
- Compact and Filter-Free Luminescence Biosensor for MobileACS nano · 2019Article
- Fluorescence lifetime imaging of upper gastrointestinal pHChemical science · 2019Article
- Towards robust and versatile single nanoparticle fiducial markers for correlative light and electron microscopy.Journal of microscopy · 2019Article
- Precise supramolecular control of surface coverage densities on polymer micro- and nanoparticles.Chemical science · 2018Article
- Single-Nanoparticle Cell Barcoding by Tunable FRET from Lanthanides to Quantum Dots.Angewandte Chemie (International ed. in English) · 2018Article
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Significant multiplexing capacity of optical time-domain coding has been recently demonstrated by tuning luminescence lifetimes of the upconversion nanoparticles called 'τ-Dots'. It provides a large dynamic range of lifetimes from microseconds to milliseconds, which allows creating large libraries of nanotags/microcarriers. However, a robust approach is required to rapidly and accurately measure the luminescence lifetimes from the relatively slow-decaying signals. Here we show a fast algorithm suitable for the microsecond region with precision closely approaching the theoretical limit and compatible with the rapid scanning cytometry technique. We exploit this approach to further extend optical time-domain multiplexing to the downconversion luminescence, using luminescence microspheres wherein lifetimes are tuned through luminescence resonance energy transfer. We demonstrate real-time discrimination of these microspheres in the rapid scanning cytometry, and apply them to the multiplexed probing of pathogen DNA strands. Our results indicate that tunable luminescence lifetimes have considerable potential in high-throughput analytical sciences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.