Evidence map›Paper›PMID 24795857›Full record

ArticleLiquid crystals reviews2013

Chemical and biological sensing using liquid crystals.

Rebecca J Carlton, Jacob T Hunter, Daniel S Miller, Reza Abbasi, Peter C Mushenheim, Lie Na Tan, Nicholas L Abbott

Abstract read
In one paragraph

Article in Liquid crystals reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

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  14. Aquatic Functional Liquid Crystals: Design, Functionalization, and Molecular Simulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  15. Article
  16. Article
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rebecca J CarltonDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706.
Jacob T HunterDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706.
Daniel S MillerDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706.
Reza AbbasiDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706.
Peter C MushenheimDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706.
Lie Na TanDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706.
Nicholas L AbbottDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706.

Funding

BIOTECHNOLOGY TRAINING PROGRAMT32GM008349 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI FOX, BRIAN G · 1989 to 2019
$22.5M
BIOMOLECULAR ANALYSIS USING LIQUID CRYSTALSR01CA108467 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI ABBOTT, NICHOLAS L · 2004 to 2013
$3.8M
Nano-Structure Surfaces and Liquid Crystal AnalysisR21CA105730 · NCI · UNIVERSITY OF WISCONSIN MADISON · PI SCHILLER, JOAN H · 2004 to 2005
$259k
NCI NIH HHS R01 CA108467NCI NIH HHS R21 CA105730NIGMS NIH HHS T32 GM008349
6 · The paper itself

Abstract

The liquid crystalline state of matter arises from orientation-dependent, non-covalent interaction between molecules within condensed phases. Because the balance of intermolecular forces that underlies formation of liquid crystals is delicate, this state of matter can, in general, be easily perturbed by external stimuli (such as an electric field in a display). In this review, we present an overview of recent efforts that have focused on exploiting the responsiveness of liquid crystals as the basis of chemical and biological sensors. In this application of liquid crystals, the challenge is to design liquid crystalline systems that undergo changes in organization when perturbed by targeted chemical and biological species of interest. The approaches described below revolve around the design of interfaces that selectively bind targeted species, thus leading to surface-driven changes in the organization of the liquid crystals. Because liquid crystals possess anisotropic optical and dielectric properties, a range of different methods can be used to read out the changes in organization of liquid crystals that are caused by targeted chemical and biological species. This review focuses on principles for liquid crystal-based sensors that provide an optical output.

Indexed as

anchoring transitionsbacteriabiological sensorsbiomolecular interfacescellschemically functionalized interfaceschemical sensorsDNAlipidsLiquid crystalsnerve agentsproteinssurfacestoxic chemicalsviruses

Identifiers

PMID24795857
PMCPMC4005293

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.