ReviewFrontiers in immunology2014
Fish allergens at a glance: variable allergenicity of parvalbumins, the major fish allergens.
Review in Frontiers in immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 194 citations in OpenAlex.
- The Efficacy of Fish as an Early Complementary Food on the Linear Growth of Infants Aged 6-7 Months: A Randomised Controlled Trial.Nutrients · 2022Trial
- Recent insights for fish allergens: novel processing techniques and detection technology.Journal of the science of food and agriculture · 2026Review
- Sebastidae-specific food allergy causing anaphylaxis: a pediatric case report and fish allergen analysis.BMC pediatrics · 2026Article
- Occupational hypersensitivity pneumonitis in salmon processing worker: novel antigenic proteins from salmon.Occupational medicine (Oxford, England) · 2026Article
- Design of a multiepitope immunotherapy for fish allergy.Scientific reports · 2026Article
- Calcium-binding proteins as allergens.Frontiers in allergy · 2026Review
- Molecular sensitization profiles and β-parvalbumin sensitization burden associated with clinical fish allergy in children.Frontiers in immunology · 2026Article
- Proteomic Characterization of Major Fish Allergy Responsive Protein Parvalbumins in Hilsa (Journal of agricultural and food chemistry · 2025Article
- Article
- Mass Spectrometry-Based Proteomics for Seafood Allergen Detection and Quantification: Current Trends and Technological Frontiers.International journal of molecular sciences · 2025Review
- Article
- A Comparison of the Structural Changes and IgG Immunobinding Activity of Parvalbumin in Salangid Icefish (Foods (Basel, Switzerland) · 2025Article
- New Perspectives on Canned Fish Quality and Safety on the Road to Sustainability.Foods (Basel, Switzerland) · 2025Review
- Fish isoallergens and variants: database compilation,Frontiers in bioinformatics · 2025Article
- Review
- Combined Integrative RNA-Seq and Serological sIgE Analysis Enhances Understanding of Fish Allergen Profiles and Diagnostic Strategy for Fish Allergy.International journal of molecular sciences · 2024Article
- Au@Ag Core-Shell Nanoparticles for Colorimetric and Surface-Enhanced Raman-Scattering-Based Multiplex Competitive Lateral Flow Immunoassay for the Simultaneous Detection of Histamine and Parvalbumin in Fish.ACS applied nano materials · 2024Article
- Microhomology-mediated end-joining Knock-In approaches to delete the allergenic domain of troutOpen research Europe · 2024Article
- Review
- Identification of Fish Species and Targeted Genetic Modifications Based on DNA Analysis: State of the Art.Foods (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fish is a common trigger of severe, food-allergic reactions. Only a limited number of proteins induce specific IgE-mediated immune reactions. The major fish allergens are the parvalbumins. They are members of the calcium-binding EF-hand protein family characterized by a conserved protein structure. They represent highly cross-reactive allergens for patients with specific IgE to conserved epitopes. These patients might experience clinical reactions with various fish species. On the other hand, some individuals have IgE antibodies directed against unique, species-specific parvalbumin epitopes, and these patients show clinical symptoms only with certain fish species. Furthermore, different parvalbumin isoforms and isoallergens are present in the same fish and might display variable allergenicity. This was shown for salmon homologs, where only a single parvalbumin (beta-1) isoform was identified as allergen in specific patients. In addition to the parvalbumins, several other fish proteins, enolases, aldolases, and fish gelatin, seem to be important allergens. New clinical and molecular insights advanced the knowledge and understanding of fish allergy in the last years. These findings were useful for the advancement of the IgE-based diagnosis and also for the management of fish allergies consisting of advice and treatment of fish-allergic patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.