ArticleFrontiers in human neuroscience2014
Cerebral pressure passivity in newborns with encephalopathy undergoing therapeutic hypothermia.
Article in Frontiers in human neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03512613 (A Pilot Study- Monitoring Cerebral Blood Flow in Neonates With Congenital Heart Defects), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Study- Monitoring Cerebral Blood Flow in Neonates With Congenital Heart Defects
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Cerebral Near Infrared Spectroscopy Monitoring in Term Infants With Hypoxic Ischemic Encephalopathy-A Systematic Review.Frontiers in neurology · 2020Pooled it
- Plasma Biomarkers of Evolving Encephalopathy and Brain Injury in Neonates with Hypoxic-Ischemic Encephalopathy.The Journal of pediatrics · 2023Observational
- Bedside and laboratory neuromonitoring in neonatal encephalopathy.Seminars in fetal & neonatal medicine · 2021Review
- Exploratory Assessment of the Relationship Between Hemoglobin Volume Phase Index, Magnetic Resonance Imaging, and Functional Outcome in Neonates with Hypoxic-Ischemic Encephalopathy.Neurocritical care · 2021Article
- Regional heterogeneity of cerebral hemodynamics in mild neonatal encephalopathy measured with multichannel near-infrared spectroscopy.Pediatric research · 2021Article
- Role of Optical Neuromonitoring in Neonatal Encephalopathy-Current State and Recent Advances.Frontiers in pediatrics · 2021Review
- Article
- Pressure passivity of cerebral mitochondrial metabolism is associated with poor outcome following perinatal hypoxic ischemic brain injury.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Article
- Ensuring signal quality of cerebral near infrared spectroscopy during continuous longterm monitoring.Journal of neuroscience methods · 2018Article
- Baroreflex dysfunction in sick newborns makes heart rate an unreliable surrogate for blood pressure changes.Pediatric research · 2016Article
- A novel technique for quantitative bedside monitoring of neurovascular coupling.Journal of neuroscience methods · 2016Article
- Wavelet coherence analysis of dynamic cerebral autoregulation in neonatal hypoxic-ischemic encephalopathy.NeuroImage. Clinical · 2016Article
- Impaired cerebral autoregulation and brain injury in newborns with hypoxic-ischemic encephalopathy treated with hypothermia.Journal of neurophysiology · 2015Article
- Editorial on emerging neuroimaging tools for studying normal and abnormal human brain development.Frontiers in human neuroscience · 2015Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
We extended our recent modification of the power spectral estimation approach to quantify spectral coherence. We tested both the standard and the modified approaches on simulated data, which showed that the modified approach was highly specific and sensitive to the coupling introduced in the simulation while the standard approach lacked these features. We also applied the modified and standard approaches to quantify the pressure passivity in 4 infants receiving therapeutic hypothermia. This was done by measuring the coupling between continuous cerebral hemoglobin differences and mean arterial blood pressure. Our results showed that the modified approach identified a lower pressure passivity index (PPI, percent time the coherence was above a predefined threshold) than the standard approach (P = 0.0027).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.