Evidence map›Paper›PMID 24795547›Full record

ArticleGynecological surgery2014

Anti-adhesion barrier gels following operative hysteroscopy for treating female infertility: a systematic review and meta-analysis.

Jan Bosteels, Steven Weyers, Ben W J Mol, Thomas D'Hooghe

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Gynecological surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02744716 (Effects of Aspirin and Intrauterine Balloon on the Post-operative Uterine Endometrial Repair and Reproductive Prognosis in Patients With Severe Intrauterine Adhesion), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02744716 nacompletednot on this map

Effects of Aspirin and Intrauterine Balloon on the Post-operative Uterine Endometrial Repair and Reproductive Prognosis in Patients With Severe Intrauterine Adhesion: a Prospective Cohort Study

TypeinterventionalSponsorFirst Affiliated Hospital, Sun Yat-Sen UniversityRan2011 to 2016Enrolled114ConditionsIntrauterine AdhesionArmsAspirin, intrauterine balloon
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Surgical management of uterine fibroids.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Knockdown of miR-27a reduces TGFβ-induced EMT and HAmerican journal of translational research · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Introduction of Female Reproductive Processes and Reproductive Diseases.Advances in experimental medicine and biology · 2021
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Jan BosteelsDepartment of Obstetrics and Gynaecology, Imeldahospitaal, Imeldalaan 9, 2820 Bonheiden, Belgium ; CEBAM, Centre for Evidence-based Medicine, the Belgian Branch of the Dutch Cochrane Centre, ACHG, Kapucijnenvoer 33, blok J bus 7001, 3000 Leuven, Belgium.
Steven WeyersUniversitaire Vrouwenkliniek, University Hospital Gent, De Pintelaan 185, 9000 Gent, Belgium.
Ben W J MolSchool of Paediatrics and Reproductive Health, The Robinson Institute, University of Adelaide, 5000 SA Adelaide, Australia.
Thomas D'HoogheLeuven University Fertility Centre, KU Leuven, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium.
Ghent University Hospital · BEImelda Hospital · BEKU Leuven · BEUniversity of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to assess the effects of any anti-adhesion barrier gel used after operative hysteroscopy for treating infertility associated with uterine cavity abnormalities. Gynecologists might use any barrier gel following operative hysteroscopy in infertile women for decreasing de novo adhesion formation; the use of any barrier gel is associated with less severe de novo adhesions and lower mean adhesion scores. Nevertheless, infertile women should be counseled that there is at the present no evidence for higher live birth or pregnancy rates. There is a lack of data for the outcome miscarriage. Preclinical studies suggest that the use of biodegradable surgical barriers may decrease postsurgical adhesion formation. Observational studies in the human report conflicting results. We searched the Cochrane Menstrual Disorders and Subfertility Specialized Register (10 April 2013), the Cochrane Central Register of Controlled Trials (

Indexed as

Adhesion preventionBarrier gelInfertilityMeta-analysisOperative hysteroscopySystematic review

Identifiers

PMID24795547
PMCPMC4003345
OpenAlexW2060760918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.