ArticleSynlett : accounts and rapid communications in synthetic organic chemistry2014
Nickel-catalyzed cross-electrophile coupling of 2-chloropyridines with alkyl bromides.
Article in Synlett : accounts and rapid communications in synthetic organic chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- Titanium-Mediated Organic Electrosynthesis.ACS catalysis · 2025Review
- Cross-Electrophile Coupling: Principles, Methods, and Applications in Synthesis.Chemical reviews · 2024Review
- Mechanical Activation of Zero-Valent Metal Reductants for Nickel-Catalyzed Cross-Electrophile Coupling.ACS catalysis · 2022Article
- Zinc-Free, Scalable Reductive Cross-Electrophile Coupling Driven by Electrochemistry in an Undivided Cell.ACS catalysis · 2022Article
- Overcoming Limitations in Decarboxylative Arylation via Ag-Ni Electrocatalysis.Journal of the American Chemical Society · 2022Article
- Leveraging the 1,3-azadiene-anhydride reaction for the synthesis of functionalized piperidines bearing up to five contiguous stereocenters.RSC advances · 2021Article
- The Power of Chemists Is in What They Can Learn, Not What They Already Know.Chembiochem : a European journal of chemical biology · 2021Article
- Article
- Deaminative Reductive Cross-Electrophile Couplings of Alkylpyridinium Salts and Aryl Bromides.Organic letters · 2019Article
- Coupling of Challenging Heteroaryl Halides with Alkyl Halides via Nickel-Catalyzed Cross-Electrophile Coupling.The Journal of organic chemistry · 2017Article
- Exhaustive Suzuki-Miyaura reactions of polyhalogenated heteroarenes with alkyl boronic pinacol esters.Chemical communications (Cambridge, England) · 2017Article
- A mild catalytic system for radical conjugate addition of nitrogen heterocycles.Chemical science · 2017Article
- Nickel-Catalyzed Reductive Conjugate Addition of Primary Alkyl Bromides to Enones To Form Silyl Enol Ethers.Organic letters · 2017Article
- Selective and Serial Suzuki-Miyaura Reactions of Polychlorinated Aromatics with Alkyl Pinacol Boronic Esters.Organic letters · 2016Article
- Nickel-Catalyzed Asymmetric Reductive Cross-Coupling between Heteroaryl Iodides and α-Chloronitriles.Journal of the American Chemical Society · 2015Article
- Methods and Mechanisms for Cross-Electrophile Coupling of Csp(2) Halides with Alkyl Electrophiles.Accounts of chemical research · 2015Article
- Reductive cross-coupling of 3-bromo-2,1-borazaronaphthalenes with alkyl iodides.Organic letters · 2014Article
- Cross-electrophile coupling: principles of reactivity and selectivity.The Journal of organic chemistry · 2014Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The synthesis of 2-alkylated pyridines by the nickel-catalyzed cross-coupling of two different electrophiles, 2-chloropyridines with alkyl bromides, is described. Compared to our previously published conditions for aryl halides, this method uses the different, more rigid bathophenanthroline ligand and is conducted at high concentration in DMF solvent. The method displays promising functional group compatibility and the conditions are orthogonal to the Stille coupling.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.