Evidence map›Paper›PMID 24795465›Full record

ReviewJournal of immunology (Baltimore, Md. : 1950)2014

Check MAIT.

Laurent Gapin

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of immunology (Baltimore, Md. : 1950), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
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  6. Mitogen-Activated Protein Kinase (MAPK) and Obesity-Related Cancer.International journal of molecular sciences · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Laurent GapinDepartment of Immunology, University of Colorado School of Medicine, Denver, CO 80206.
University of Colorado Denver · US

Funding

iNKT Cell Recognition of Endogenous Lipid AntigensR01AI092108 · NIAID · UNIVERSITY OF COLORADO DENVER · PI GAPIN, LAURENT · 2011 to 2014
$1.5M
NIAID NIH HHS AI092108NIAID NIH HHS R01 AI092108
6 · The paper itself

Abstract

The evolutionary conservation of T lymphocyte subsets bearing αβ TCRs using invariant α-chains is indicative of unique and important functions. Among these T lymphocytes, NKT cells that express an invariant TCRα-chain and recognize lipid Ags presented by the nonclassical MHC class I molecule CD1d are probably the most studied. However, a new population of evolutionarily conserved T cells with another invariant TCRα rearrangement was recently characterized. These cells, which are very abundant in humans, tend to reside in mucosal tissues and, therefore, were named mucosal-associated invariant T (MAIT) cells. Until recently, little was known about MAIT cells; however, several recent advances in our understanding of MAIT cell characteristics and functions secure their upcoming rise to fame in the immunology field and in clinical practice.

Indexed as

AnimalsAntigens, CD1HumansImmunity, MucosalIntestinal MucosaNatural Killer T-CellsReceptors, Antigen, T-Cell, alpha-betaT-LymphocytesAntigens, CD1Receptors, Antigen, T-Cell, alpha-beta

Identifiers

PMID24795465
PMCPMC4025967
OpenAlexW4242320876

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.