ReviewHuman molecular genetics2014
Next generation sequencing techniques in neurological diseases: redefining clinical and molecular associations.
Review in Human molecular genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- Cost-effectiveness of a gene sequencing test for Alzheimer's disease in Ontario.Journal of community genetics · 2023Article
- Disorders of the adrenal cortex: Genetic and molecular aspects.Frontiers in endocrinology · 2022Review
- Genetic architecture of common non-Alzheimer's disease dementias.Neurobiology of disease · 2020Review
- Review
- Genetic landscape of autism spectrum disorder in Vietnamese children.Scientific reports · 2020Article
- A Customized Next-Generation Sequencing-Based Panel to Identify Novel Genetic Variants in Dementing Disorders: A Pilot Study.Neural plasticity · 2020Article
- Epigenetics of the Synapse in Neurodegeneration.Current neurology and neuroscience reports · 2019Review
- Heritability and genetic variance of dementia with Lewy bodies.Neurobiology of disease · 2019Article
- Phosphoinositides: Regulators of Nervous System Function in Health and Disease.Frontiers in molecular neuroscience · 2019Review
- Review
- Problems of Unknown Significance: Counseling in the Era of Next Generation Sequencing.Balkan journal of medical genetics : BJMG · 2018Article
- Genetic test utilization and diagnostic yield in adult patients with neurological disorders.Neurogenetics · 2018Article
- ERLIN1 mutations cause teenage-onset slowly progressive ALS in a large Turkish pedigree.European journal of human genetics : EJHG · 2018Article
- Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program.Biomarkers in medicine · 2017Article
- Deep brain stimulation for dystonia: a novel perspective on the value of genetic testing.Journal of neural transmission (Vienna, Austria : 1996) · 2017Review
- Landscape of Pleiotropic Proteins Causing Human Disease: Structural and System Biology Insights.Human mutation · 2017Article
- Next-generation sequencing in neuromuscular diseases.Current opinion in neurology · 2016Review
- Exome Sequencing Fails to Identify the Genetic Cause of Aicardi Syndrome.Molecular syndromology · 2016Article
- Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD.Autophagy · 2016Article
- Phylogeographic analysis of hemorrhagic fever with renal syndrome patients using multiplex PCR-based next generation sequencing.Scientific reports · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The development of next-generation sequencing technologies has allowed for the identification of several new genes and genetic factors in human genetics. Common results from the application of these technologies have revealed unexpected presentations for mutations in known disease genes. In this review, we summarize the major contributions of exome sequencing to the study of neurodegenerative disorders and other neurological conditions and discuss the interface between Mendelian and complex neurological diseases with a particular focus on pleiotropic events.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.