ReviewCurrent opinion in biotechnology2014
Synthetic analog and digital circuits for cellular computation and memory.
Review in Current opinion in biotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed.
- Enzyme-Free DNA Logic Circuit with Single-Color Readout for Dual Biomarker Detection.Applied biochemistry and biotechnology · 2026Article
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- Characterization of recombinase activity across cellular growth phases.Scientific reports · 2025Article
- Epigenetic memory: The role of the crosstalk between histone modifications and DNA methylation.Computational and structural biotechnology journal · 2025Review
- CRISPR perfect adaptation for robust control of cellular immune and apoptotic responses.Nucleic acids research · 2024Article
- A Genetic Circuit Design for Targeted Viral RNA Degradation.Bioengineering (Basel, Switzerland) · 2023Article
- Self-organized computation in the far-from-equilibrium cell.Biophysics reviews · 2022Review
- A synthetic distributed genetic multi-bit counter.iScience · 2021Article
- Synthetic neural-like computing in microbial consortia for pattern recognition.Nature communications · 2021Article
- Topologies of synthetic gene circuit for optimal fold change activation.Nucleic acids research · 2021Article
- Protease circuits for processing biological information.Nature communications · 2020Article
- Concerted localization-resets precede YAP-dependent transcription.Nature communications · 2020Article
- Controlling spatiotemporal pattern formation in a concentration gradient with a synthetic toggle switch.Molecular systems biology · 2020Article
- Protein assembly systems in natural and synthetic biology.BMC biology · 2020Review
- Programming Escherichia coli to function as a digital display.Molecular systems biology · 2020Article
- CRISPR-Based Synthetic Transcription Factors In Vivo: The Future of Therapeutic Cellular Programming.Cell systems · 2020Review
- Synthetic biology for improving cell fate decisions and tissue engineering outcomes.Emerging topics in life sciences · 2019Article
- Metabolic perceptrons for neural computing in biological systems.Nature communications · 2019Article
- A portable epigenetic switch for bistable gene expression in bacteria.Scientific reports · 2019Article
- Genetic circuits to engineer tissues with alternative functions.Journal of biological engineering · 2019Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Biological computation is a major area of focus in synthetic biology because it has the potential to enable a wide range of applications. Synthetic biologists have applied engineering concepts to biological systems in order to construct progressively more complex gene circuits capable of processing information in living cells. Here, we review the current state of computational genetic circuits and describe artificial gene circuits that perform digital and analog computation. We then discuss recent progress in designing gene networks that exhibit memory, and how memory and computation have been integrated to yield more complex systems that can both process and record information. Finally, we suggest new directions for engineering biological circuits capable of computation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.