Evidence map›Paper›PMID 24794292›Full record

ArticleThe international journal of cardiovascular imaging2014

Dose reduction for coronary calcium scoring with hybrid and model-based iterative reconstruction: an ex vivo study.

Annemarie M den Harder, Martin J Willemink, Ronald L A W Bleys, Pim A de Jong, Ricardo P J Budde, Arnold M R Schilham, Tim Leiner

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Article in The international journal of cardiovascular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  9. Cardiovascular imaging 2014 in the International Journal of Cardiovascular Imaging.The international journal of cardiovascular imaging · 2015
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Annemarie M den HarderDepartment of Radiology, Utrecht University Medical Center, E01.132, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Martin J Willemink
Ronald L A W Bleys
Pim A de Jong
Ricardo P J Budde
Arnold M R Schilham
Tim Leiner

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the influence of dose reduction on coronary calcium scoring using hybrid and model-based iterative reconstruction (IR) techniques.

methodsFifteen ex vivo hearts were scanned in a phantom representing an average adult person at routine dose and three levels of dose reduction; 27, 55 and 82% reduced-dose, respectively. All images were reconstructed using filtered back-projection (FBP), hybrid IR (iDose4, levels 1, 4 and 7) as well as model-based IR iterative model reconstruction (IMR, levels 1, 2 and 3). Agatston, mass and volume scores found with iDose4 and IMR were compared to FBP reconstruction (routine dose) as well as objective image quality.

resultsWith FBP calcium scores remained unchanged at 82% reduced dose. With IR Agatston scores differed significantly at routine dose, using IMR level 3 and iDose4 level 7, and at 82% reduced dose, using IMR levels 1-3 and iDose4 level 7. The maximum median difference was 5.3%. Mass remained unchanged at reduced dose levels while volume was significantly lower at 82% reduced dose with IMR (maximum median difference 5.0%). Objective image quality improved with IR, at 82% reduced dose the CNR of iDose4 level 7 was similar to the reference dose CNR, and IMR levels 1-3 resulted in an even higher CNR.

conclusionCalcium scores were not affected by radiation-dose reduction with FBP and low levels of hybrid IR. Objective image quality increased significantly using hybrid and model-based IR. Therefore low level hybrid IR has the potential to reduce radiation-dose of coronary calcium scoring with up to 82%.

Indexed as

AlgorithmsMultidetector Computed TomographyRadiation DosageCoronary AngiographyCoronary Artery DiseaseCoronary VesselsHumansPhantoms, ImagingPredictive Value of TestsRadiographic Image Interpretation, Computer-AssistedSeverity of Illness IndexVascular Calcification

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.