ReviewJournal of Zhejiang University. Science. B2014
The polyadenylation code: a unified model for the regulation of mRNA alternative polyadenylation.
Review in Journal of Zhejiang University. Science. B, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Involvement of oncomiRs miR-23, miR-24, and miR-27 in the regulation of alternative polyadenylation in glioblastoma via CFIm25 cleavage factor.Metabolic brain disease · 2024Article
- Full-Length RNA Sequencing Provides Insights into Goldfish Evolution under Artificial Selection.International journal of molecular sciences · 2023Article
- Template-Independent Poly(A)-Tail Decay and RNASEL as Potential Cellular Biomarkers for Prostate Cancer Development.Cancers · 2022Article
- Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.Neuron · 2022Article
- Fine gene expression regulation by minor sequence variations downstream of the polyadenylation signal.Molecular biology reports · 2021Article
- Identification and Characterization of Transcripts Regulated by Circadian Alternative Polyadenylation in Mouse Liver.G3 (Bethesda, Md.) · 2018Article
- A comprehensive analysis of 3' end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and polyadenylation.Genome research · 2016Article
- Poly(A) code analyses reveal key determinants for tissue-specific mRNA alternative polyadenylation.RNA (New York, N.Y.) · 2016Article
- Differential expression of endogenous plant cell wall degrading enzyme genes in the stick insect (Phasmatodea) midgut.BMC genomics · 2014Article
- Transcription: the epicenter of gene expression.Journal of Zhejiang University. Science. B · 2014Article
- mRNA stability in the nucleus.Journal of Zhejiang University. Science. B · 2014Review
- CFIm25 in Solid Tumors: Current Research Progress.Technology in cancer research & treatmentReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The majority of eukaryotic genes produce multiple mRNA isoforms with distinct 3' ends through a process called mRNA alternative polyadenylation (APA). Recent studies have demonstrated that APA is dynamically regulated during development and in response to environmental stimuli. A number of mechanisms have been described for APA regulation. In this review, we attempt to integrate all the known mechanisms into a unified model. This model not only explains most of previous results, but also provides testable predictions that will improve our understanding of the mechanistic details of APA regulation. Finally, we briefly discuss the known and putative functions of APA regulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.