ReviewDrug discovery today2014
Approaches to in vitro tissue regeneration with application for human disease modeling and drug development.
Review in Drug discovery today, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Advancing cell therapies with artificial intelligence and synthetic biology.Current opinion in biomedical engineering · 2025Article
- Multi-Organ Microphysiological Systems Targeting Specific Organs for Recapitulating Disease Phenotypes via Organ Crosstalk.Small science · 2024Article
- Use and application of organ-on-a-chip platforms in cancer research.Journal of cell communication and signaling · 2023Review
- Multiparametric Material Functionality of Microtissue-Based In Vitro Models as Alternatives to Animal Testing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Review
- A Roadmap of In Vitro Models in Osteoarthritis: A Focus on Their Biological Relevance in Regenerative Medicine.Journal of clinical medicine · 2021Review
- Microengineered 3D pulmonary interstitial mimetics highlight a critical role for matrix degradation in myofibroblast differentiation.Science advances · 2020Article
- Modeling neoplastic disease with spheroids and organoids.Journal of hematology & oncology · 2020Review
- Organoids-on-a-chip.Science (New York, N.Y.) · 2019Article
- The Application of Induced Pluripotent Stem Cells in Cardiac Disease Modeling and Drug Testing.Journal of cardiovascular translational research · 2018Review
- Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- 3D Bioprinting for Vascularized Tissue Fabrication.Annals of biomedical engineering · 2017Review
- Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators.Scientific reports · 2016Article
- Functional peptide KP24 enhances submandibular gland tissue growthRegenerative therapy · 2016Article
- Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing.ALTEX · 2016Review
- From cardiac tissue engineering to heart-on-a-chip: beating challenges.Biomedical materials (Bristol, England) · 2015Review
- Engineering myocardial tissue patches with hierarchical structure-function.Annals of biomedical engineering · 2015Review
- A cost-effective fluorescence mini-microscope for biomedical applications.Lab on a chip · 2015Article
- Collagen immobilization on ultra-thin nanofiber membrane to promoteJournal of tissue engineeringArticle
- Human iPSC-derived cardiomyocytes and tissue engineering strategies for disease modeling and drug screening.Biotechnology advancesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Reliable in vitro human disease models that capture the complexity of in vivo tissue behaviors are crucial to gain mechanistic insights into human disease and enable the development of treatments that are effective across broad patient populations. The integration of stem cell technologies, tissue engineering, emerging biomaterials strategies and microfabrication processes, as well as computational and systems biology approaches, is enabling new tools to generate reliable in vitro systems to study the molecular basis of human disease and facilitate drug development. In this review, we discuss these recently developed tools and emphasize opportunities and challenges involved in combining these technologies toward regenerative science.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.