ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2014
Proton magnetic resonance spectroscopy of skeletal muscle: a comparison of two quantitation techniques.
Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- Water-suppression cycling 3-T cardiacNMR in biomedicine · 2021Article
- How Imaging Can Assist with Diagnosis and Monitoring of Disease in Myositis.Current rheumatology reports · 2020Review
- Searching for a better formulation to enhance muscle bioenergetics: A randomized controlled trial of creatine nitrate plus creatinineFood science & nutrition · 2019Article
- Quantitative MRI Musculoskeletal Techniques: An Update.AJR. American journal of roentgenology · 2019Review
- Reduced skeletal muscle phosphocreatine concentration in type 2 diabetic patients: a quantitative image-based phosphorus-31 MR spectroscopy study.American journal of physiology. Endocrinology and metabolism · 2018Article
- When are metabolic ratios superior to absolute quantification? A statistical analysis.NMR in biomedicine · 2017Article
- [Technique of proton and phosphorous MR spectroscopy].Der Radiologe · 2017Review
- Imaging: seeing muscle in new ways.Current opinion in rheumatology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
RATIONALE AND
objectivesThe aim of this study was to develop and compare two methods for quantification of metabolite concentrations in human skeletal muscle using phased-array receiver coils at 3T. MATERIALS AND
methodsWater suppressed and un-suppressed spectra were recorded from the quadriceps muscle (vastus medialis) in 8 healthy adult volunteers, and from a calibration phantom containing 69mM/L N-acetyl aspartate. Using the phantom replacement technique, trimethylamine specifically [TMA] and creatine [Cr] concentrations were estimated, and compared to those values obtained by using the water reference method.
resultsQuadriceps [TMA] concentrations were 9.5±2.4 and 9.6±4.1mmol/kg wet weight using the phantom replacement and water referencing methods respectively, while [Cr] concentrations were 26.8±12.2 and 24.1±5.3mmol/kg wet weight respectively.
conclusionsReasonable agreement between water referencing and phantom replacement methods was found, although for [Cr] variation was significantly higher for the phantom replacement technique. The relative advantages and disadvantages of each approach are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.