Evidence map›Paper›PMID 24792855›Full record

ReviewLancet (London, England)2014

Outdoor air pollution and asthma.

Michael Guarnieri, John R Balmes

Abstract readReview
In one paragraph

Review in Lancet (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 647 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
647citing papers in PubMed, 5 pooled it
44.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

647 citing papers in PubMed, 5 syntheses or guidelines pooled it, 1,824 citations in OpenAlex.

  1. Pooled it
  2. Chemical constituents of PMEuropean journal of pediatrics · 2025
    Pooled it
  3. Long-Term PMAnnals of the American Thoracic Society · 2025
    Pooled it
  4. Association between air pollution and allergic upper respiratory diseases: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  5. Pooled it
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587 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Michael GuarnieriDepartment of Medicine, University of California, San Francisco, CA, USA; Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA.
John R BalmesDepartment of Medicine, University of California, San Francisco, CA, USA; Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA. Electronic address: jbalmes@medsfgh.ucsf.edu.
University of California, Berkeley · USUniversity of California, San Francisco · US

Funding

MUTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007185 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI David J Erle, LAURENCE HUANG · 1985 to 2026
$24.6M
NHLBI NIH HHS T32 HL007185
6 · The paper itself

Abstract

Traffic and power generation are the main sources of urban air pollution. The idea that outdoor air pollution can cause exacerbations of pre-existing asthma is supported by an evidence base that has been accumulating for several decades, with several studies suggesting a contribution to new-onset asthma as well. In this Series paper, we discuss the effects of particulate matter (PM), gaseous pollutants (ozone, nitrogen dioxide, and sulphur dioxide), and mixed traffic-related air pollution. We focus on clinical studies, both epidemiological and experimental, published in the previous 5 years. From a mechanistic perspective, air pollutants probably cause oxidative injury to the airways, leading to inflammation, remodelling, and increased risk of sensitisation. Although several pollutants have been linked to new-onset asthma, the strength of the evidence is variable. We also discuss clinical implications, policy issues, and research gaps relevant to air pollution and asthma.

Indexed as

Air PollutantsAir PollutionAsthmaEnvironmental ExposureGasesHealth PolicyHumansParticulate MatterRisk FactorsVehicle EmissionsAir PollutantsGasesParticulate MatterVehicle Emissions

Identifiers

PMID24792855
PMCPMC4465283
OpenAlexW2083753594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.