ArticleJournal of neurology2014
Diffusion tensor imaging in blepharospasm and blepharospasm-oromandibular dystonia.
Article in Journal of neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Structural magnetic resonance imaging in dystonia: A systematic review of methodological approaches and findings.European journal of neurology · 2022Pooled it
- White matter microstructural alterations correlate with clinical characteristics in craniocervical dystonia.Neuroradiology · 2026Article
- Distinct Roles of Cerebellar Afferent and Efferent Fiber Tracts in Craniocervical Dystonia.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Multidimensional structural analyses revealed a correlation between thalamic atrophy and white matter degeneration in idiopathic dystonia.Brain communications · 2025Article
- Progressive thalamic nuclear atrophy in blepharospasm and blepharospasm-oromandibular dystonia.Brain communications · 2024Article
- Cortico-Subcortical White Matter Bundle Changes in Cervical Dystonia and Blepharospasm.Biomedicines · 2023Article
- The pathogenesis of blepharospasm.Frontiers in neurology · 2023Review
- Cortico-basal ganglia networks dysfunction associated with disease severity in patients with idiopathic blepharospasm.Frontiers in neuroscience · 2023Article
- Evaluation of ocular blood flow by Doppler ultrasound in patients with essential blepharospasm.Journal of ultrasound · 2022Article
- Altered Structural Brain Network Topology in Patients With Primary Craniocervical Dystonia.Frontiers in neurology · 2022Article
- Cortical and Subcortical Structural Abnormalities in Patients With Idiopathic Cervical and Generalized Dystonia.Frontiers in neuroimaging · 2022Article
- Thalamic structural connectivity profiles in blepharospam/Meige's syndrome.NeuroImage. Clinical · 2022Article
- Sex related differences in nonmotor symptoms of patients with idiopathic blepharospasm.Scientific reports · 2021Article
- The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia.Science translational medicine · 2021Article
- Machine Learning for Predicting Individual Severity of Blepharospasm Using Diffusion Tensor Imaging.Frontiers in neuroscience · 2021Article
- Does the network model fits neurophysiological abnormalities in blepharospasm?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Review
- Thalamostriatal degeneration contributes to dystonia and cholinergic interneuron dysfunction in a mouse model of Huntington's disease.Acta neuropathologica communications · 2020Article
- Cervical Dystonia Is Associated With Aberrant Inhibitory Signaling Within the Thalamus.Frontiers in neurology · 2020Article
- Structural Brain Changes in Blepharospasm: A Cortical Thickness and Diffusion Tensor Imaging Study.Frontiers in neuroscience · 2020Article
- Stroke-induced resolution of primary blepharospasm: evidence for the lenticular nucleus as a control candidate.BMJ case reports · 2018Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patterns of white matter (WM) abnormalities and correlation with clinical features in patients with blepharospasm (BSP) and patients with blepharospasm-oromandibular dystonia (BOM) remain unknown. Using voxel-based analysis, diffusion behaviors of WM including fractional anisotropy (FA), mean diffusivity (MD) and eigenvalues were compared between 20 BSP patients vs. 11 healthy controls (HCs) and 11 patients with BOM vs. 11 HCs. Correlation analyses were performed to assess possible association between diffusion behaviors of significantly different areas and clinical measures. Compared with HCs, BSP patients showed significant FA reductions in the left anterior lobe of cerebellum. Significant increases of MD and radial diffusivity (RD) were detected in right lentiform nucleus and thalamus. Significantly decreased FA in the right precuneus of parietal lobe, increased MD in the right lentiform nucleus and insula, and increased axial diffusivity in the right insula were observed in BOM patients. The FA values in the WM of left cerebellum negatively correlated with disease severity in BSP patients measured by JRS (r = -0.655, p = 0.002). The FA values in the right parietal WM negatively correlated with disease duration in BOM patients (r = -0.745, p = 0.008). Both BSP and BOM are related to microstructural abnormalities of WM in the basal ganglia. WM changes outside the basal ganglia may present trait features that are specific for individual dystonia phenotype. The correlation between FA abnormalities and symptom severity suggests that DTI parameters might be of clinical value in assessing and following disability in BSP patients.
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