Evidence map›Paper›PMID 24792591›Full record

ArticleEuropean radiology2014

Low tube voltage and low contrast material volume cerebral CT angiography.

Song Luo, Long Jiang Zhang, Felix G Meinel, Chang Sheng Zhou, Li Qi, Andrew D McQuiston, U Joseph Schoepf, Guang Ming Lu

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In one paragraph

Article in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

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  11. Intraoperative 2D/3D Image Registration via Differentiable X-ray Rendering.Proceedings. IEEE Computer Society Conference on Computer Vision and Pattern Recognition · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Song LuoDepartment of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, 210002, China.
Long Jiang Zhang
Felix G Meinel
Chang Sheng Zhou
Li Qi
Andrew D McQuiston
U Joseph Schoepf
Guang Ming Lu
Nanjing General Hospital of Nanjing Military Command · CNNanjing University · CNMedical University of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the image quality, radiation dose and diagnostic accuracy of low kVp and low contrast material volume cerebral CT angiography (CTA) in intracranial aneurysm detection.

methodsOne hundred twenty patients were randomly divided into three groups (n = 40 for each): Group A, 70 ml iodinated contrast agent/120 kVp; group B, 30 ml/100 kVp; group C, 30 ml/80 kVp. The CT numbers, noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were measured in the internal carotid artery (ICA) and middle cerebral artery (MCA). Subjective image quality was evaluated. For patients undergoing DSA, diagnostic accuracy of CTA was calculated with DSA as reference standard and compared.

resultsCT numbers of ICA and MCA were higher in groups B and C than in group A (P < 0.01). SNR and CNR in groups A and B were higher than in group C (both P < 0.05). There was no difference in subjective image quality among the three groups (P = 0.939). Diagnostic accuracy for aneurysm detection among these groups had no statistical difference (P = 1.00). Compared with group A, the radiation dose of groups B and C was decreased by 45% and 74%.

conclusionCerebral CTA at 100 or 80 kVp using 30 ml contrast agent can obtain diagnostic image quality with a low radiation dose while maintaining the same diagnostic accuracy for aneurysm detection. KEY POINTS: • Cerebral CTA is feasible using 100/80 kVp and 30 ml contrast agent. • This approach obtains diagnostic image quality with 45-74% radiation dose reduction. • Diagnostic accuracy for intracranial aneurysm detection seems not to be compromised.

Indexed as

AdultAgedCerebral AngiographyContrast MediaDose-Response Relationship, DrugFemaleFollow-Up StudiesHumansInjections, IntravenousIntracranial AneurysmIohexolMaleMiddle AgedRadiation DosageReproducibility of ResultsRetrospective StudiesContrast MediaIohexoliopromide

Identifiers

PMID24792591
OpenAlexW1965743354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.