Evidence map›Paper›PMID 24791915›Full record

ReviewSports medicine (Auckland, N.Z.)2014

Dietary nitrate supplementation and exercise performance.

Andrew M Jones

4 registry-linked trialsOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Sports medicine (Auckland, N.Z.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 186 papers, 23 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
186citing papers in PubMed, 23 pooled it
81.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02319356 early_phase1unknown statusnot on this mapstarted 2015, after this paper: background citation

Does Dietary Nitrate Supplementation Improve Aerobic Performance in Colorectal Cancer? A Pilot Study

TypeinterventionalSponsorRoyal Surrey County Hospital NHS Foundation TrustRan2015 to 2015Enrolled70ConditionsColorectal CancerArmsBeetroot juice, Placebo beetroot juice
NCT02850367 nacompletednot on this mapstarted 2016, after this paper: background citation

The Effect of NO Precursors on Physiological Responses to Exercise

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2016 to 2021Enrolled63ConditionsPhysiologyArmsNitrate, Nitrate and L-Arginine, Nitrate and L-Citrulline, Placebo, Evaluation of post-ischemic vascular reactivity
NCT03371966 nacompletednot on this mapstarted 2017, after this paper: background citation

The Effects of Chronic Dietary Nitrate Supplementation on Constant Work Rate Exercise in High Functioning Middle Aged and Older Adults

TypeinterventionalSponsorWake Forest UniversityRan2017 to 2019Enrolled29ConditionsAgingArmsHigh Nitrate Beetroot Juice, Low Nitrate Beetroot Juice
NCT03944226 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Is Dietary Nitrate Effective in Reducing Aerobic Glycolysis (AG) in Breast Cancer? - A Longitudinal Study Using Specialist Magnetic Resonance (MR) Methods

TypeinterventionalSponsorUniversity of AberdeenRan2019 to 2020Enrolled16ConditionsMalignant Breast Tissue NeoplasmArmsBeetroot juice
3 · Its place in the literature

Who cites it

186 citing papers in PubMed, 23 syntheses or guidelines pooled it, 409 citations in OpenAlex.

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126 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Andrew M JonesSport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, St. Luke's Campus, Exeter, EX1 2LU, UK, a.m.jones@exeter.ac.uk.
University of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary nitrate is growing in popularity as a sports nutrition supplement. This article reviews the evidence base for the potential of inorganic nitrate to enhance sports and exercise performance. Inorganic nitrate is present in numerous foodstuffs and is abundant in green leafy vegetables and beetroot. Following ingestion, nitrate is converted in the body to nitrite and stored and circulated in the blood. In conditions of low oxygen availability, nitrite can be converted into nitric oxide, which is known to play a number of important roles in vascular and metabolic control. Dietary nitrate supplementation increases plasma nitrite concentration and reduces resting blood pressure. Intriguingly, nitrate supplementation also reduces the oxygen cost of submaximal exercise and can, in some circumstances, enhance exercise tolerance and performance. The mechanisms that may be responsible for these effects are reviewed and practical guidelines for safe and efficacious dietary nitrate supplementation are provided.

Indexed as

Dietary SupplementsSports Nutritional Physiological PhenomenaAthletic PerformanceEnergy MetabolismExerciseExercise ToleranceHumansMuscle, SkeletalNitratesOxygen ConsumptionNitrates

Identifiers

PMID24791915
PMCPMC4008816
OpenAlexW2012172244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.