ArticleJournal of toxicologic pathology2014
Spontaneous nephroblastoma with lung metastasis in a rat.
Article in Journal of toxicologic pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- A case report of RccHanJournal of toxicologic pathology · 2021Article
- Nephroblastoma in a Sprague Dawley rat unrelated to titanium dioxide nanoparticle exposure in utero.Veterinary medicine and science · 2021Article
- A case of spontaneous nephroblastoma characterized by two distinct morphologies in a Slc:CD(SD)IGS rat.Journal of toxicologic pathology · 2020Article
- Anaplastic nephroblastoma with peritoneal metastasis in an adult female Sprague Dawley rat.Journal of toxicologic pathology · 2020Article
- Spontaneous nephroblastoma with oncocytic differentiation in a Japanese White rabbit.Journal of toxicologic pathology · 2017Article
- Obstructive nephropathy induced with DL-potassium hydrogen tartrate in F344 rats.Journal of toxicologic pathology · 2015Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This report describes a spontaneous nephroblastoma with lung metastasis in a 10-week-old male Crl:CD(SD) rat. Macroscopically, a white mass in the kidney and two white masses in the lung were observed. Histopathologically, the renal mass was located in the cortex of a kidney, and it caused pressure on the surrounding renal parenchyma. Three components could be distinguished in the tumor: blastemal, epithelial (primitive glomerular/tubular structures) and mesenchymal (neoplastic connective tissues) elements. Immunohistochemically, the tumor cells were positive for Wilms tumor 1 protein (WT1) and vimentin. Metastasis was found in the lung. Thus, the case was diagnosed as a nephroblastoma with lung metastasis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.