Evidence map›Paper›PMID 24790993›Full record

ReviewBioMed research international2014

Worldwide dissemination of the NDM-type carbapenemases in Gram-negative bacteria.

Laurent Dortet, Laurent Poirel, Patrice Nordmann

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 250 papers.

0numbers the graph read from it
0cells of the map it votes in
250citing papers in PubMed
19.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

250 citing papers in PubMed, 481 citations in OpenAlex.

  1. Article
  2. Article
  3. Multicenter outbreak of plasmid-encodedAntimicrobial agents and chemotherapy · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Phenotypic and Genotypic Characterization of Carbapenem-ResistantInternational journal of microbiology · 2026
    Article
  15. Genomic Insights intoMicroorganisms · 2025
    Article
  16. Clinical carbapenem-resistantMicrobiology spectrum · 2025
    Article
  17. Article
  18. Article
  19. Emergence and Polyclonal Dissemination of blaEmerging infectious diseases · 2025
    Article
  20. Review

190 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Laurent DortetINSERM U914 "Emerging Resistance to Antibiotics", 78 Avenue du Général Leclerc, 94270 Le Kremlin-Bicêtre, France.
Laurent PoirelINSERM U914 "Emerging Resistance to Antibiotics", 78 Avenue du Général Leclerc, 94270 Le Kremlin-Bicêtre, France ; Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, 3 Rue Albert Gockel, 1700 Fribourg, Switzerland.
Patrice NordmannINSERM U914 "Emerging Resistance to Antibiotics", 78 Avenue du Général Leclerc, 94270 Le Kremlin-Bicêtre, France ; Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, 3 Rue Albert Gockel, 1700 Fribourg, Switzerland.
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of one of the most recently described carbapenemases, namely, the New Delhi metallo-lactamase (NDM-1), constitutes a critical and growingly important medical issue. This resistance trait compromises the efficacy of almost all lactams (except aztreonam), including the last resort carbapenems. Therapeutical options may remain limited mostly to colistin, tigecycline, and fosfomycin. The main known reservoir of NDM producers is the Indian subcontinent whereas a secondary reservoir seems to have established the Balkans regions and the Middle East. Although the spread of bla NDM-like genes (several variants) is derived mostly by conjugative plasmids in Enterobacteriaceae, this carbapenemase has also been identified in P. aeruginosa and Acinetobacter spp. Acinetobacter sp. may play a pivotal role for spreading bla NDM genes for its natural reservoir to Enterobacteriaceae. Rapid diagnostic techniques (Carba NP test) and screening of carriers are the cornerstone to try to contain this outbreak which threatens the efficacy of the modern medicine.

Indexed as

beta-LactamasesCommunicable Diseases, EmergingDisease OutbreaksGlobal HealthGram-Negative BacteriaGram-Negative Bacterial InfectionsHumansIncidencebeta-lactamase NDM-1beta-Lactamases

Identifiers

PMID24790993
PMCPMC3984790
OpenAlexW2089011135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.