Evidence map›Paper›PMID 24790681›Full record

ArticleThe open prostate cancer journal2010

Ganoderic Acid DM: An Alternative Agent for the Treatment of Advanced Prostate Cancer.

Benjamin M Johnson, Bently P Doonan, Faisal F Radwan, Azizul Haque

Abstract read
In one paragraph

Article in The open prostate cancer journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Exploring the Therapeutic Potential ofJournal of clinical medicine · 2024
    Review
  4. Article
  5. A Review ofBiomolecules · 2022
    Review
  6. Peptide Modification Diminishes HLA Class II-restricted CD4International journal of molecular sciences · 2022
    Article
  7. Lucidumol A, Purified Directly fromEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Misconstrued versatility of Ganoderma lucidum: a key player in multi-targeted cellular signaling.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Review
  13. Article
  14. Ganoderic Acid in the treatment of prostate cancer.Jundishapur journal of natural pharmaceutical products · 2012
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Benjamin M JohnsonDepartment of Microbiology and Immunology, Charles Darby Children's Research Institute, and Hollings Cancer Center, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425.
Bently P DoonanDepartment of Microbiology and Immunology, Charles Darby Children's Research Institute, and Hollings Cancer Center, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425.
Faisal F RadwanDepartment of Microbiology and Immunology, Charles Darby Children's Research Institute, and Hollings Cancer Center, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425.
Azizul HaqueDepartment of Microbiology and Immunology, Charles Darby Children's Research Institute, and Hollings Cancer Center, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425.

Funding

Disruption of HLA Class II-Mediated Immune Recognition of B-Cell LymphomasR01CA129560 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HAQUE, AZIZUL · 2009 to 2013
$1.5M
NCI NIH HHS R01 CA129560
6 · The paper itself

Abstract

Prostate cancer is the most commonly diagnosed cancer in men and accounts for significant morbidity and mortality in the western world. While traditional therapies are effective at clearing early stage cancer, they often fail to treat late stage metastatic disease. Thus, an effective therapy that targets prostate tumor growth and metastasis is desired for alleviating the disease and improving patient outcomes. Natural extracts have been the focus of recent investigation, particularly those with reduced cellular toxicity to healthy tissue. In this review, we discuss one potential candidate, ganoderic acid, an extract from the

Indexed as

5-α-reductaseAndrogenChemotherapyDihydrotestosteroneGanoderic acidsOsteoclastogenesisProstate cancer

Identifiers

PMID24790681
PMCPMC4002166

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.