ArticleInternational journal of nanomedicine2014
Synthesis and in vitro antineoplastic evaluation of silver nanoparticles mediated by Agrimoniae herba extract.
Article in International journal of nanomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Nanomaterial-enabled drug transport systems: a comprehensive exploration of current developments and future avenues in therapeutic delivery.3 Biotech · 2024Review
- Antifungal Activity ofJournal of functional biomaterials · 2023Article
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- A review of nanomaterials from synthetic and natural molecules for prospective breast cancer nanotherapy.Frontiers in pharmacology · 2023Review
- The Application Effect of Traditional Chinese Medicine Nursing on General Anesthesia Combined with Epidural Anesthesia and Electric Resection for the Treatment of Bladder Cancer and Its Influence on Tumor Markers.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Biomedical Applications of Chinese Herb-Synthesized Silver Nanoparticles by Phytonanotechnology.Nanomaterials (Basel, Switzerland) · 2021Review
- The therapeutic effects of Agrimonia eupatoria L.Physiological research · 2020Review
- Review
- Biosynthesized Silver Nanoparticle (AgNP) FromFrontiers in microbiology · 2019Article
- Antibacterial, anticancer and antioxidant potential of silver nanoparticles engineered usingIET nanobiotechnology · 2018Article
- Antibacterial potential of silver nanoparticles biosynthesised usingIET nanobiotechnology · 2017Article
- Biomimetic synthesis of antimicrobial silver nanoparticles using in vitro-propagated plantlets of a medicinally important endangered species: Phlomis bracteosa.International journal of nanomedicine · 2016Article
- Thidiazuron-enhanced biosynthesis and antimicrobial efficacy of silver nanoparticles via improving phytochemical reducing potential in callus culture of Linum usitatissimum L.International journal of nanomedicine · 2016Article
- Article
- Enhanced stability and antibacterial efficacy of a traditional Chinese medicine-mediated silver nanoparticle delivery system.International journal of nanomedicine · 2014Article
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5 authors.
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Abstract
A rapid synthesis of silver nanoparticles (AgNPs) using Agrimoniae herba extract as reducing agent and stabilizer (A. herba-conjugated AgNPs [AH-AgNPs]) were designed, characterized, and evaluated for antitumor therapy feasibility. In this study, critical factors in the preparation of silver nanoparticles, including extraction time, reaction temperature, the concentration of AgNO3, and A. herba extract amount, were investigated using ultraviolet-visible spectroscopy. AH-AgNPs with well-defined spherical shape, homogeneous distributional small size (30.34 nm), narrow polydispersity index (0.142), and high negative zeta potential (-36.8 mV) were observed by transmission electron microscopy and dynamic light scattering. Furthermore, the results of X-ray diffraction and Fourier-transform infrared spectroscopy further indicated successful preparation of AH-AgNPs. Acceptable long-term storage stability of AH-AgNPs was also confirmed. More importantly, AH-AgNPs displayed significantly higher antiproliferative effect against a human lung carcinoma cell line (A549 cells) compared with A. herba extract and bare AgNPs prepared by sodium citrate. The half-maximal inhibitory concentrations of AH-AgNPs, bare AgNPs, and A. herba extract were 38.13 μg · mL(-1), 184.87 μg · mL(-1), and 1.147 × 10(4) μg · mL(-1), respectively. It is suggested that AH-AgNPs exhibit a strong antineoplastic effect on A549 cells, pointing to feasibility of antitumor treatment in the future.
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