Evidence map›Paper›PMID 24790273›Full record

ArticleSleep2014

Obstructive sleep apnea in obese community-dwelling children: the NANOS study.

María Luz Alonso-Álvarez, José Aurelio Cordero-Guevara, Joaquin Terán-Santos, Mónica Gonzalez-Martinez, María José Jurado-Luque, Jaime Corral-Peñafiel, Joaquin Duran-Cantolla, Leila Kheirandish-Gozal, David Gozal

2 registry-linked trialsOpen access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Sleep, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01322763 unknown statusnot on this map

Prevalence of Sleep Apnea/Hypopnea Syndrome in Obese Children. The Significance of Hormonal Factors

TypeobservationalSponsorSociedad Española de Neumología y Cirugía TorácicaRan2008 to 2012Enrolled200ConditionsSleep Apnea, Children, Obesity
NCT03449550 nacompletednot on this mapstarted 2015, after this paper: background citation

Validity and Cost-effectiveness Analysis of a Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea in Children (DINISAS)

TypeinterventionalSponsorHospital Universitario ArabaRan2015 to 2020Enrolled320ConditionsObstructive Sleep ApneaArmsHome Respiratory Polygraphy (HRP), Standard Polysomnography (PSG)
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 150 citations in OpenAlex.

  1. Guideline
  2. Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline.The Journal of clinical endocrinology and metabolism · 2017 · on this map
    Guideline
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

María Luz Alonso-ÁlvarezSleep Unit, Hospital Universitario de Burgos, Burgos, Spain ; CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain ; Hospital Universitario de Burgos (HUBU), Burgos, Spain.
José Aurelio Cordero-GuevaraSleep Unit, Hospital Universitario de Burgos, Burgos, Spain ; CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain ; Hospital Universitario de Burgos (HUBU), Burgos, Spain.
Joaquin Terán-SantosSleep Unit, Hospital Universitario de Burgos, Burgos, Spain ; CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain ; Hospital Universitario de Burgos (HUBU), Burgos, Spain.
Mónica Gonzalez-MartinezSleep Unit, Hospital Universitario de Burgos, Burgos, Spain ; Hospital Universitario Valdecilla, Santander, Cantabria, Spain.
María José Jurado-LuqueSleep Unit, Hospital Universitario de Burgos, Burgos, Spain ; CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain ; Hospital Val D'Hebron, Barcelona, Spain.
Jaime Corral-PeñafielSleep Unit, Hospital Universitario de Burgos, Burgos, Spain ; CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain ; Hospital San Pedro de Alcantara, Cáceres, Spain.
Joaquin Duran-CantollaSleep Unit, Hospital Universitario de Burgos, Burgos, Spain ; CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain ; Research Department, Hospital Universitario Araba, BioAraba, Universidad del Pais Vasco, Medicine Department, Vitoria, Spain.
Leila Kheirandish-GozalSection of Sleep Medicine, Department of Pediatrics, Comer Children's Hospital, Pritzker School of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL.
David GozalSection of Sleep Medicine, Department of Pediatrics, Comer Children's Hospital, Pritzker School of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL.
Instituto de Salud Carlos III · ESComer Children's Hospital · USUniversity of the Basque Country · ES

Funding

Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
NEUROCOGNITIVE FUNCTION IN SNORING CHILDRENR01HL065270 · NHLBI · UNIVERSITY OF LOUISVILLE · PI GOZAL, DAVID · 1999 to 2014
$5.0M
NCATS NIH HHS UL1 TR000430NHLBI NIH HHS HL-65270
6 · The paper itself

Abstract

introductionObesity in children is assumed to serve as a major risk factor in pediatric obstructive sleep apnea syndrome (OSAS). However, the prevalence of OSAS in otherwise healthy obese children from the community is unknown.

aimTo determine the prevalence of OSAS in obese children identified and recruited from primary care centers.

methodsA cross-sectional, prospective, multicenter study. Spanish children ages 3-14 y with a body mass index (BMI) greater than or equal to the 95th percentile for age and sex were randomly selected, and underwent medical history, snoring, and Pediatric Sleep Questionnaire (PSQ) assessments, as well as physical examination, nasopharyngoscopy, and nocturnal polysomnography (NPSG) recordings.

resultsTwo hundred forty-eight children (54.4% males) with mean age of 10.8 ± 2.6 y were studied with a BMI of 28.0 ± 4.7 kg/m(2) corresponding to 96.8 ± 0.6 percentile when adjusted for age and sex. The mean respiratory disturbance index (RDI), obstructive RDI (ORDI), and obstructive apnea-hypopnea index (OAHI) were 5.58 ± 9.90, 5.06 ± 9.57, and 3.39 ± 8.78/h total sleep time (TST), respectively. Using ≥ 3/h TST as the cutoff for the presence of OSAS, the prevalence of OSAS ranged from 21.5% to 39.5% depending on whether OAHI, ORDI, or RDI were used.

conclusionsThe prevalence of obstructive sleep apnea syndrome (OSAS) in obese children from the general population is high. Obese children should be screened for the presence of OSAS. ClinicalTrials.gov identifier: NCT01322763.

Indexed as

AdolescentBody Mass IndexChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleMass ScreeningObesityPhysical ExaminationPolysomnographyPrevalencePrimary Health CareProspective StudiesRisk Factorsadenotonsillar hypertrophychildrenobesityprevalencesleep apnea

Identifiers

PMID24790273
PMCPMC3985101
OpenAlexW2091152074

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.