ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Sex, age, and cognitive correlates of asymmetries in thickness of the cortical mantle across the life span.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
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Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium.Proceedings of the National Academy of Sciences of the United States of America · 2018Pooled it
- Effect of in-painting on cortical thickness measurements in multiple sclerosis: A large cohort study.Human brain mapping · 2015Trial
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- Deep learning models identify brain changes during the progression of Alzheimer's disease.NPJ systems biology and applications · 2026Article
- Brain age gradients as intermediate phenotypes linking plasma p-tau217 to cognition in community-dwelling older adults.NPJ dementia · 2026Article
- Changes in voxel-wise gray matter asymmetry over time.Frontiers in neuroscience · 2025Article
- Exploring the relationship among Alzheimer's disease, aging and cognitive scores through neuroimaging-based approach.Scientific reports · 2024Article
- Large-scale analysis of structural brain asymmetries during neurodevelopment: Associations with age and sex in 4265 children and adolescents.Human brain mapping · 2024Article
- Using a deep generation network reveals neuroanatomical specificity in hemispheres.Patterns (New York, N.Y.) · 2024Article
- Regional Tau Deposition Reflects Different Pathways of Subsequent Neurodegeneration and Memory Decline in Cognitively Normal Older Adults.Annals of neurology · 2024Article
- Histopathologic brain age estimation via multiple instance learning.Acta neuropathologica · 2023Article
- Tracing the development and lifespan change of population-level structural asymmetry in the cerebral cortex.eLife · 2023Article
- Structural and functional asymmetry of the neonatal cerebral cortex.Nature human behaviour · 2023Article
- Asymmetries and hemispheric interaction in the auditory system of elderly people.Frontiers in neuroimaging · 2023Review
- Characterization of the angular gyrus in an older adult population: a multimodal multilevel approach.Brain structure & function · 2023Article
- Article
- Mapping Complex Brain Torque Components and Their Genetic Architecture and Phenomic Associations in 24,112 Individuals.Biological psychiatry · 2022Article
- Is it left or is it right? A classification approach for investigating hemispheric differences in low and high dimensionality.Brain structure & function · 2022Article
- Mapping brain asymmetry in health and disease through the ENIGMA consortium.Human brain mapping · 2022Review
- Increased representation of the non-dominant hand in pianists demonstrated by measurement of 3D morphology of the central sulcus.Psychoradiology · 2021Article
Corrections and comments
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5 authors.
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Abstract
We assessed the correlations of age, sex, and cognitive performance with measures of asymmetry in cortical thickness on high-resolution MRIs in 215 healthy human children and adults, 7-59 years of age. A left > right asymmetry in thickness of the cortical mantle was present throughout the entire lateral, dorsal, and mesial surfaces of the frontal lobe, extending into primary sensory, superior parietal, and anterior superior temporal cortices. A right > left asymmetry was present in the lateral, mesial, and dorsal surfaces of the posterior temporal, parietal, and occipital cortices, as well as in the entire inferior surface of the brain. An exaggerated left > right asymmetry was detected in females in anterior brain regions, and an exaggerated right > left asymmetry was detected in males in the orbitofrontal, inferior parietal, and inferior occipital cortices. Weaker moderating effects of sex were scattered along the mesial surface of the brain. Age significantly moderated asymmetry measures in the inferior sensorimotor, inferior parietal, posterior temporal, and inferior occipital cortices. The age × asymmetry interaction derived from a steeper decline in cortical thickness with age in the right hemisphere than in the left on the lateral surface, whereas it derived from a steeper decline with age in the left hemisphere than in the right on the mesial surface. Finally, measures of performance on working memory and vocabulary tasks improved with increasing magnitudes of normal asymmetries in regions thought to support these cognitive capacities.
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