Evidence map›Paper›PMID 24790142›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2014

Perivascular adipose tissue and coronary vascular disease.

Meredith Kohr Owen, Jillian N Noblet, Daniel J Sassoon, Abass M Conteh, Adam G Goodwill, Johnathan D Tune

Abstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Obesity Duration and Cardiometabolic Disease.Arteriosclerosis, thrombosis, and vascular biology · 2023
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Effects of an Indoor Cycling Program on Cardiometabolic Factors in Women with Obesity vs. Normal Body Weight.International journal of environmental research and public health · 2020
    Article
  9. Article
  10. Review
  11. Review
  12. Cardiovascular risk and obesity.Diabetology & metabolic syndrome · 2019
    Review
  13. Emerging Roles for Adipose Tissue in Cardiovascular Disease.Arteriosclerosis, thrombosis, and vascular biology · 2018
    Review
  14. Article
  15. Cardiovascular consequences of metabolic syndrome.Translational research : the journal of laboratory and clinical medicine · 2017
    Review
  16. Review
  17. Regulation of Coronary Blood Flow.Comprehensive Physiology · 2017
    Review
  18. Vitamin D Deficiency Accelerates Coronary Artery Disease Progression in Swine.Arteriosclerosis, thrombosis, and vascular biology · 2016
    Article
  19. Perivascular adipose tissue and inflammation.Obesity (Silver Spring, Md.) · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Meredith Kohr OwenFrom the Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill (M.K.O.); and Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis (J.N.N., D.J.S., A.M.C., A.G.G., J.D.T.).
Jillian N NobletFrom the Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill (M.K.O.); and Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis (J.N.N., D.J.S., A.M.C., A.G.G., J.D.T.).
Daniel J SassoonFrom the Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill (M.K.O.); and Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis (J.N.N., D.J.S., A.M.C., A.G.G., J.D.T.).
Abass M ContehFrom the Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill (M.K.O.); and Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis (J.N.N., D.J.S., A.M.C., A.G.G., J.D.T.).
Adam G GoodwillFrom the Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill (M.K.O.); and Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis (J.N.N., D.J.S., A.M.C., A.G.G., J.D.T.).
Johnathan D TuneFrom the Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill (M.K.O.); and Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis (J.N.N., D.J.S., A.M.C., A.G.G., J.D.T.). jtune@iu.edu.

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Indiana Medical Scientist/Engineer Training ProgramT32GM077229 · NIGMS · INDIANA UNIVERSITY INDIANAPOLIS · PI GASTON, BENJAMIN, HERBERT, BRITTNEY-SHEA · 2008 to 2022
$6.0M
Cardiovascular effects of GLP-1 in obesity/metabolic syndromeR01HL117620 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI MATHER, KIEREN J, TUNE, JOHNATHAN D · 2013 to 2017
$3.4M
Mechanisms of coronary microvascular dysfunction in metabolic syndromeR01HL092245 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI TUNE, JOHNATHAN D · 2009 to 2012
$1.5M
Indiana Clinical and Translational Science Institute-T32 Program TL1TL1TR000162 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI SHEKHAR, ANANTHA · 2012 to 2013
$264k
NCATS NIH HHS TL1 TR000162NCATS NIH HHS UL1 TR001108NHLBI NIH HHS HL092245NHLBI NIH HHS HL117620NHLBI NIH HHS HL117620-S1NHLBI NIH HHS R01 HL092245NHLBI NIH HHS R01 HL117620NIGMS NIH HHS T32 GM077229
6 · The paper itself

Abstract

Coronary perivascular adipose tissue is a naturally occurring adipose tissue depot that normally surrounds the major coronary arteries on the surface of the heart. Although originally thought to promote vascular health and integrity, there is a growing body of evidence to support that coronary perivascular adipose tissue displays a distinct phenotype relative to other adipose depots and is capable of producing local factors with the potential to augment coronary vascular tone, inflammation, and the initiation and progression of coronary artery disease. The purpose of the present review is to outline previous findings about the cardiovascular effects of coronary perivascular adipose tissue and the potential mechanisms by which adipose-derived factors may influence coronary vascular function and the progression of atherogenesis.

Indexed as

Adipose TissueAnimalsCoronary Artery DiseaseCoronary VesselsGene Expression RegulationHumansParacrine CommunicationPhenotypeSignal Transductionadipokinesadipose tissueobesity

Identifiers

PMID24790142
PMCPMC4103953

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.