Evidence map›Paper›PMID 24789985›Full record

ReviewPhysiology (Bethesda, Md.)2014

Alcohol abuse: critical pathophysiological processes and contribution to disease burden.

Patricia E Molina, Jason D Gardner, Flavia M Souza-Smith, Annie M Whitaker

Open access · greenAbstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Nephroprotective effects of ethanol leaf extract ofResearch in pharmaceutical sciences · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. The effect of CHeliyon · 2023
    Article
  15. Review
  16. Article
  17. Alcohol and Skeletal Muscle in Health and Disease.Alcohol research : current reviews · 2023
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Patricia E MolinaDepartment of Physiology and Alcohol and Drug Abuse Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Jason D Gardner
Flavia M Souza-Smith
Annie M Whitaker
Louisiana State University Health Sciences Center New Orleans · US

Funding

Translational Research/Education ComponentP60AA009803 · NIAAA · LSU HEALTH SCIENCES CENTER · PI DAVID A WELSH · 2004 to 2026
$42.6M
BIOMEDICAL ALCOHOL RESEARCH TRAINING PROGRAMT32AA007577 · NIAAA · LSU HEALTH SCIENCES CENTER · PI PATRICIA E. MOLINA · 1999 to 2026
$9.6M
PILOT--IMPACT OF ALCOHOLISM ON AIDS ASOCIATED MUSCLE WASTINGP50AA009803 · NIAAA · LOUISIANA STATE UNIV HSC NEW ORLEANS · PI NELSON, STEVE · 1994 to 2003
$7.2M
Regulation of Nutrient Sensing and Muscle Wasting by AlcoholR01AA011290 · NIAAA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LANG, CHARLES H. · 1997 to 2011
$3.5M
Regulation of Nutrient Sensing and Muscle Wasting by AlcoholR37AA011290 · NIAAA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LANG, CHARLES H. · 2012 to 2021
$3.4M
Impact of alcohol intoxication on lymphatic contractile mechanismsF32AA021049 · NIAAA · LSU HEALTH SCIENCES CENTER · PI SOUZA, FLAVIA MOREIRA · 2012 to 2014
$163k
NIAAA NIH HHS AA-021049NIAAA NIH HHS AA-07577NIAAA NIH HHS AA-09803NIAAA NIH HHS AA-11290NIAAA NIH HHS F32 AA021049NIAAA NIH HHS P50 AA009803NIAAA NIH HHS R01 AA011290NIAAA NIH HHS R37 AA011290NIAAA NIH HHS T32 AA007577PHS HHS UAA-021995A
6 · The paper itself

Abstract

Alcohol abuse; the most common and costly form of drug abuse, is a major contributing factor to many disease categories. The alcohol-attributable disease burden is closely related to the average volume of alcohol consumption, with dose-dependent relationships between amount and duration of alcohol consumption and the incidence of diabetes mellitus, hypertension, cardiovascular disease, stroke, and pneumonia. The frequent occurrence of alcohol use disorders in the adult population and the significant and widespread detrimental organ system effects highlight the importance of recognizing and further investigating the pathophysiological mechanisms underlying alcohol-induced tissue and organ injury.

Indexed as

Alcohol DrinkingAlcoholismAlcohol-Related DisordersAnimalsCost of IllnessHumans

Identifiers

PMID24789985
PMCPMC4046814
OpenAlexW2163040921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.