ReviewThe Journal of clinical investigation2014
Emerging therapies for food allergy.
Review in The Journal of clinical investigation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01904604 (Epicutaneous Immunotherapy), which is not on this map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Epicutaneous Immunotherapy (EPIT) for Peanut Allergy: A Randomized, Double-Blind, Placebo-Controlled, Phase II Study in Children and Adults (DAIT COFAR6)
Who cites it
21 citing papers in PubMed, 53 citations in OpenAlex.
- Early oral immunotherapy in peanut-allergic preschool children is safe and highly effective.The Journal of allergy and clinical immunology · 2017Trial
- Sublingual immunotherapy for peanut allergy: Long-term follow-up of a randomized multicenter trial.The Journal of allergy and clinical immunology · 2015Trial
- HIV-1 Tat immunization restores immune homeostasis and attacks the HAART-resistant blood HIV DNA: results of a randomized phase II exploratory clinical trial.Retrovirology · 2015Trial
- Clinical Proteomics Applied to Food Allergy.Advances in experimental medicine and biology · 2026Review
- Review
- Angled Insertion of Microneedles for Targeted Antigen Delivery to the Epidermis.Pharmaceutics · 2022Article
- Article
- Egg Allergy: Diagnosis and Immunotherapy.International journal of molecular sciences · 2020Review
- New Perspectives in Food Allergy.International journal of molecular sciences · 2020Review
- Modulating Shrimp Tropomyosin-Mediated Allergy: Hypoallergen DNA Vaccines Induce Regulatory T Cells to Reduce Hypersensitivity in Mouse Model.International journal of molecular sciences · 2019Article
- Regional Differences in Food Allergies.Clinical reviews in allergy & immunology · 2019Review
- Eosinophilic esophagitis during sublingual and oral allergen immunotherapy.Current opinion in allergy and clinical immunology · 2019Review
- Food Allergies: Current and Future Treatments.Medicina (Kaunas, Lithuania) · 2019Review
- A network-based approach for identifying suitable biomarkers for oral immunotherapy of food allergy.BMC bioinformatics · 2019Article
- Hypoallergenic Proteins for the Treatment of Food Allergy.Current allergy and asthma reports · 2019Review
- The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype.Science translational medicine · 2019Article
- Current perspectives on tree nut allergy: a review.Journal of asthma and allergy · 2018Review
- The rise of food allergy: Environmental factors and emerging treatments.EBioMedicine · 2016Review
- Current Options for the Treatment of Food Allergy.Pediatric clinics of North America · 2015Review
- Translating new developments in eosinophilic esophagitis pathogenesis into clinical practice.Current treatment options in gastroenterology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Food allergy is a common condition for which there are currently no approved treatments except avoidance of the allergenic food and treatment of accidental reactions. There are several potential treatments that are under active investigation in animal and human studies, but it is not yet clear what the best approach may be. Here, we review approaches that are currently in clinical trials, including oral, sublingual, and epicutaneous immunotherapy, immunotherapy combined with anti-IgE, and Chinese herbal medicine as well as approaches that are in preclinical or early clinical investigation, including modified protein immunotherapy, adjuvants, DNA vaccines, and helminth administration. We discuss the importance of fully exploring the risks and benefits of any treatment before it is taken to general clinical practice and the need for clarity about the goals of treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.